ShantiMoon 5-HTP | 5-Hydroxytryptophan from Griffonia Seed | Serotonin Support Capsules | 60 Count*
$76.95 USD
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Estimated delivery between December 16 and December 20.
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Additional Information
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Manufacturer Country
USA
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Product Amount
60 caps
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Gross Weight
0.25lb (113g)
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Suggested Use
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Take two (2) capsules once a day as a dietary supplement. For best results, take 2030 min before a meal with an 8oz (236 ml) glass of water or as directed by your healthcare professional.
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Caution
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Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
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Warning
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Keep out of reach of children. Do not use if the safety seal is damaged or missing. Store in a cool, dry place.
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User Insights
Benefits of ShantiMoon 5-HTP | 5-Hydroxytryptophan from Griffonia Seed | Serotonin Support Capsules | 60 Count*
Discover the key benefits that make our product stand out
Promoting Emotional Stability
Support Serotonin Precursor Metabolism
Help Manage Occasional Stress
Support Restful Sleep Quality
About ShantiMoon 5-HTP | 5-Hydroxytryptophan from Griffonia Seed | Serotonin Support Capsules | 60 Count*
ShantiMoon 5-HTP – Natural Serotonin Support for Mood and Emotional Well-Being*
Discover the natural approach to supporting emotional wellness with ShantiMoon 5-HTP, a premium dietary supplement featuring 5-Hydroxytryptophan (5-HTP) derived from Griffonia simplicifolia seeds. This 60-capsule formula provides a naturally-sourced precursor to serotonin that may help support healthy mood balance*, promote emotional well-being*, and contribute to overall mental wellness* through the body's own biochemical pathways.
Made in the USA, this thoughtfully formulated supplement recognizes that while 5-HTP occurs naturally in the body, some individuals may benefit from supplementation* to help maintain optimal serotonin levels*. As a direct precursor to serotonin—the neurotransmitter associated with mood, sleep, and appetite regulation—5-HTP represents a clean, holistic approach* to supporting the body's natural production of this important brain chemical*.
5-Hydroxytryptophan (5-HTP) is an amino acid naturally produced in the body from tryptophan (an essential amino acid from dietary protein). In the brain, 5-HTP converts to serotonin, which plays crucial roles in regulating mood, sleep patterns, appetite, and various other physiological and psychological functions*. Supplementing with 5-HTP bypasses the rate-limiting step in serotonin synthesis, potentially making more of this precursor available for conversion to serotonin*.
Griffonia simplicifolia, a West African plant, is the primary natural source of 5-HTP used in dietary supplements. The seeds of this woody climbing shrub contain high concentrations of 5-HTP, making it an ideal botanical source for supplementation. Unlike synthetic production methods, Griffonia-derived 5-HTP provides a plant-based, naturally-occurring form of this important compound.
Research published in scientific journals has examined 5-HTP supplementation for various applications related to mood and well-being*. Studies have explored its potential role in supporting healthy mood balance*, promoting restful sleep patterns*, and contributing to appetite regulation*. While individual results vary and more research is always needed, the existing body of evidence suggests 5-HTP may offer natural support* for those seeking to maintain emotional wellness*.
The formula includes calcium (as calcium carbonate), which may contribute to overall wellness* while serving as an excipient in the formulation. The capsules are encased in gelatin, making them easy to swallow, while magnesium stearate serves as a flow agent ensuring consistent manufacturing quality.
The serotonin connection to overall well-being is well-established in neuroscience. Serotonin influences numerous aspects of human experience—from mood and emotional state to sleep quality, appetite, digestion, and even pain perception. While serotonin itself cannot cross the blood-brain barrier when supplemented orally, its precursor 5-HTP can*, making supplementation a viable approach for supporting the body's natural serotonin production*.
Individual needs vary considerably when it comes to serotonin support. Factors including genetics, diet (particularly tryptophan intake), stress levels, light exposure, exercise habits, and various other influences affect serotonin production and function. Some individuals may find that supplemental support helps them maintain optimal balance*, particularly during challenging periods or seasonal changes.
Important: This is a dietary supplement supporting general wellness*. It is not intended to diagnose, treat, cure, or prevent any disease, including depression, anxiety, insomnia, or any mental health condition. Individuals with diagnosed mental health conditions should work with qualified healthcare providers for appropriate treatment. Do not use as a replacement for prescribed medications without medical supervision.
Understanding the Top 4 Pain Points
Pain Point #1: Low Mood and Emotional Challenges
Persistent low mood affects millions of people, creating a heavy emotional burden that impacts every aspect of life. While clinical depression requires professional treatment, many individuals experience subclinical mood concerns—feelings of being "down," lacking enthusiasm, experiencing emotional flatness, or struggling with general unhappiness that doesn't rise to the level of diagnosed depression but still significantly affects quality of life.
The serotonin connection to mood has been extensively studied. While the relationship is complex and not fully understood, research has established that serotonin plays important roles in mood regulation*. Low serotonin levels have been associated with mood challenges*, though it's important to note that mood is influenced by multiple neurotransmitters, hormones, life circumstances, and other factors—not serotonin alone.
Modern lifestyle factors may affect serotonin synthesis. Chronic stress depletes neurotransmitter reserves, inadequate dietary protein reduces available amino acid precursors, poor sleep disrupts neurotransmitter production cycles, and sedentary behavior affects various biochemical processes* including potentially serotonin metabolism. These accumulated modern stressors create conditions where the body's natural serotonin production* may not meet demand.
The emotional well-being impact of suboptimal serotonin extends beyond just "feeling sad." People describe feeling emotionally fragile, reactive to minor stressors, unable to experience joy in activities they once enjoyed, struggling with irritability, and generally feeling that life lacks color and vibrancy. This emotional flatness affects relationships, work performance, self-care motivation, and overall life satisfaction.
Treatment concerns and preferences influence supplement interest. Prescription antidepressants, while effective for many, come with potential side effects, require ongoing medical management, and may not be necessary or appropriate for subclinical mood concerns. Many individuals prefer trying natural approaches first*, particularly for mild mood support*, before considering pharmaceutical interventions.
The search for balance drives interest in natural mood support*. While serious mood disorders require professional care, those experiencing mild mood fluctuations or seeking proactive mood wellness support* may find value in supplements that support the body's natural neurotransmitter production*. The goal is maintaining emotional balance and resilience* rather than treating disease.
Finding natural approaches that support the body's serotonin production* addresses the need for mood wellness support* while respecting the body's natural biochemistry and offering a gentler first-line approach for those with mild mood concerns.
Pain Point #2: Sleep Difficulties and Disrupted Rest Patterns
Sleep problems are epidemic in modern society, with millions struggling to fall asleep easily, stay asleep through the night, achieve restorative deep sleep, or wake feeling refreshed. Poor sleep affects every aspect of health and functioning—mood, cognitive performance, immune resilience, metabolic health, and overall quality of life all suffer when sleep is inadequate or poor quality.
The serotonin-sleep connection is well-established through research. Serotonin serves as a precursor to melatonin, the primary sleep-regulating hormone. When serotonin levels are adequate, the body can convert appropriate amounts to melatonin* when darkness signals it's time for sleep. Insufficient serotonin may therefore affect the body's ability to produce adequate melatonin* and maintain healthy sleep-wake cycles*.
Multiple sleep challenges affect different individuals. Some struggle primarily with sleep onset—lying awake unable to quiet racing thoughts and relax into sleep. Others fall asleep easily but wake frequently during the night or too early in the morning. Some experience non-restorative sleep—spending adequate time in bed but waking feeling unrefreshed. Each pattern may involve different underlying mechanisms, but serotonin's role in sleep regulation* means supporting adequate levels may benefit various sleep concerns*.
The modern sleep crisis stems from lifestyle factors that disrupt natural sleep patterns. Blue light from screens suppresses melatonin production, irregular schedules confuse circadian rhythms, stress keeps the nervous system activated when it should be winding down, and stimulants consumed too late affect sleep quality. These factors all potentially impact the serotonin-melatonin pathway* that regulates healthy sleep.
The cumulative effects of poor sleep extend far beyond tiredness. Chronic sleep deprivation impairs immune function, disrupts appetite regulation and metabolism, affects emotional regulation (making people more irritable and reactive), impairs cognitive function and memory, and increases risk for various health concerns. The desperation for quality sleep drives interest in any safe intervention that might help.
Natural sleep support preferences lead many to explore supplements before stronger pharmaceutical sleep medications. While prescription sleep aids have their place, they often come with side effects including next-day grogginess, dependency risks, and simply not feeling like "natural sleep." Those seeking to support their body's natural sleep processes* may prefer approaches that work with—rather than override—the body's own sleep-regulation systems.
Finding natural support for the serotonin-melatonin pathway* that regulates healthy sleep cycles addresses the widespread need for better rest without the concerns associated with stronger sleep medications, particularly for those with mild to moderate sleep challenges.
Pain Point #3: Appetite Dysregulation and Emotional Eating
Appetite control challenges affect millions struggling with food cravings, emotional eating, inability to feel satisfied despite eating, constant thoughts about food, or difficulty maintaining healthy eating patterns. While appetite is influenced by numerous factors—hormones, blood sugar, habits, emotions, environment—serotonin plays a recognized role in appetite regulation* and satiety signaling*.
The serotonin-appetite link has been studied extensively. Research has found that serotonin appears to promote feelings of satiety* (satisfaction after eating) and may influence food preferences*. Low serotonin levels have been associated with increased carbohydrate cravings*, particularly for simple carbs and sweets. This connection helps explain why mood and appetite often seem linked—the same neurotransmitter affects both.
Emotional eating patterns create frustrating cycles. Stress, anxiety, sadness, or boredom trigger urges to eat—not from physical hunger but for emotional comfort. The temporary mood boost from eating (particularly carbohydrates, which may briefly increase serotonin*) reinforces the pattern, creating psychological and potentially biochemical associations between emotions and eating that become difficult to break.
Carbohydrate cravings specifically may have biochemical underpinnings beyond just "lack of willpower." When serotonin is low, the body may crave carbohydrates* because consuming them triggers insulin release, which affects amino acid transport in ways that temporarily increase tryptophan availability to the brain and subsequent serotonin production*. This creates a self-medication pattern where people instinctively reach for carbs when serotonin needs support.
Weight management implications make appetite regulation important for many. Excess calorie consumption driven by inadequate satiety signals, emotional eating, or constant cravings contributes to weight gain that affects health, mobility, confidence, and quality of life. While supplements alone don't cause weight loss, supporting healthy appetite regulation* may help some individuals better adhere to appropriate eating patterns as part of comprehensive lifestyle approaches.
The cycle-breaking challenge frustrates those trying to establish healthier eating patterns. When biochemical factors (like potentially low serotonin) drive cravings and eating behaviors, willpower alone often proves insufficient. Addressing underlying neurochemical aspects* may help create conditions where healthier choices become more manageable and sustainable.
Finding natural support for serotonin levels that play a role in appetite regulation* addresses one piece of the complex appetite puzzle, potentially helping some individuals better manage cravings and emotional eating patterns* as part of comprehensive wellness approaches.
Pain Point #4: Stress, Anxiety, and Emotional Overwhelm
Chronic stress and anxiety have become defining features of modern life. The constant pressure of work demands, financial concerns, relationship challenges, health worries, and the relentless pace of contemporary existence create sustained psychological stress that affects mental, emotional, and physical well-being. While clinical anxiety disorders require professional treatment, many people experience subclinical anxiety—persistent worry, tension, emotional reactivity, and stress intolerance that impacts quality of life.
The neurotransmitter connection to stress resilience involves multiple brain chemicals, with serotonin playing a recognized role. Research has found that adequate serotonin appears to support emotional regulation*, help buffer stress responses*, and contribute to overall stress resilience*. Conversely, low serotonin has been associated with increased anxiety* and reduced ability to cope with stressors.
The stress-serotonin cycle can become self-perpetuating. Chronic stress may deplete serotonin and other neurotransmitters, while low serotonin reduces stress resilience*, making individuals more vulnerable to stress impacts. This creates a downward spiral where stress worsens neurochemistry, which in turn reduces capacity to handle stress, leading to more stress impacts.
Physical manifestations of stress and anxiety affect daily life significantly. Muscle tension, headaches, digestive distress, sleep disruption, fatigue, difficulty concentrating, and feeling "on edge" or unable to relax all stem from overactive stress responses. These physical symptoms themselves create additional stress, compounding the problem.
The functioning impact of anxiety and emotional overwhelm affects work performance, relationships, social engagement, and self-care capacity. When anxiety is high, decision-making becomes impaired, concentration suffers, interpersonal interactions feel more difficult, and even basic tasks can feel overwhelming. The reduced functioning itself becomes a source of distress and frustration.
Coping strategy limitations lead to interest in additional support. While stress management techniques—meditation, exercise, therapy, sleep hygiene, and lifestyle modifications—are essential and effective, many people seek additional biochemical support*, particularly natural options that may help the body better manage its stress responses* without the side effects of pharmaceutical anxiolytics.
Finding natural support for neurotransmitter levels involved in stress resilience and emotional regulation* addresses the need for additional tools in managing modern life's unavoidable stresses, potentially helping maintain better emotional balance* and stress coping capacity*.
How ShantiMoon 5-HTP Provides Support*
Natural Mood Support Through Serotonin Precursor*
5-HTP's mechanism as a direct precursor to serotonin provides straightforward biochemical support. When you consume 5-HTP, it crosses the blood-brain barrier and is converted to serotonin in the brain*, offering direct support for serotonin synthesis*. Research published in Alternative Medicine Review examined 5-HTP's role in supporting mood*, finding evidence for its effectiveness in various studies.
Multiple research studies have examined 5-HTP for mood support. A review in Neuropsychiatric Disease and Treatment examined clinical trials finding that 5-HTP supplementation was associated with improvements in mood parameters* in various populations. While more research is needed and individual responses vary, the evidence supports 5-HTP's potential role in mood wellness*.
The natural approach appeals to those preferring to work with the body's existing pathways. Rather than artificially manipulating neurotransmitter activity (as some pharmaceuticals do), 5-HTP provides a building block the body naturally uses*, allowing the body's own regulatory systems to convert it to serotonin as needed*. This respects the body's wisdom while providing support where synthesis may be inadequate.
Griffonia simplicifolia sourcing provides botanical origin for the 5-HTP, derived from the seeds of this African plant naturally high in this compound. This plant-based sourcing creates an extract that provides 5-HTP in forms the body recognizes*, rather than synthetic alternatives.
Calcium's supporting role shouldn't be overlooked—this mineral supports various neurological functions* including nerve signal transmission*, contributing to the formula's comprehensive support for nervous system wellness*.
Individual responses vary significantly, with some people noticing mood improvements* within weeks while others may need longer or may not respond as robustly. Factors including baseline serotonin status, diet, stress levels, sleep quality, exercise, and genetic variations all influence outcomes. Consistent use over 4-12 weeks typically provides the best assessment of individual response.
By providing direct serotonin precursor support through naturally-sourced 5-HTP, ShantiMoon addresses one of the biochemical factors that may affect mood, offering natural support for emotional well-being.
Sleep Quality Support Through the Serotonin-Melatonin Pathway*
The serotonin-to-melatonin conversion is a well-established biochemical pathway. Serotonin serves as the precursor to melatonin—the pineal gland converts serotonin to melatonin* in response to darkness signals. When serotonin levels are adequate, this conversion can proceed efficiently*, supporting healthy melatonin production* and sleep-wake cycle regulation*.
Research on 5-HTP and sleep has examined its potential to support sleep quality. Studies have found that 5-HTP supplementation may help support healthy sleep patterns*, possibly through its role in melatonin production* as well as serotonin's own involvement in sleep architecture and REM sleep regulation*.
The timing consideration for sleep support often involves evening dosing, though individual responses vary. Some practitioners suggest taking 5-HTP earlier in the day to allow time for serotonin production that will later convert to melatonin at night*, while others recommend evening use closer to bedtime. Individual experimentation under healthcare provider guidance may help identify optimal timing.
Sleep architecture effects may extend beyond just falling asleep. Serotonin appears to play roles in sleep cycle regulation*, including REM sleep which is crucial for emotional processing and memory consolidation. Supporting adequate serotonin* may therefore contribute to more restorative sleep quality*, not just sleep quantity.
The non-sedating approach distinguishes 5-HTP from direct sleep aids. Rather than forcing sleep through sedation, 5-HTP supports the body's natural sleep regulation processes* by providing precursors for the neurotransmitters involved in healthy sleep-wake cycles*. This may result in more natural-feeling sleep that doesn't create morning grogginess.
Complementary practices enhance 5-HTP's sleep benefits*. Good sleep hygiene—consistent schedules, darkness at night, screen reduction before bed, stress management—works synergistically with serotonin support* to optimize sleep quality. The supplement addresses biochemical aspects while lifestyle factors address behavioral and environmental influences.
By supporting adequate serotonin production that can convert to melatonin, ShantiMoon 5-HTP may help promote healthy sleep patterns and sleep quality as part of comprehensive sleep wellness approaches.
Appetite Regulation and Satiety Support*
Serotonin's role in appetite regulation has been documented in numerous studies. Research published in journals including Nutrition Reviews has examined how serotonin affects eating behaviors, finding that it appears to promote satiety*, influence meal termination*, and potentially affect food preferences* particularly regarding carbohydrates.
The carbohydrate craving connection to serotonin provides a plausible mechanism for how 5-HTP might help. Studies suggest that low serotonin may be associated with increased carbohydrate cravings*, particularly for simple carbs and sweets. By supporting adequate serotonin levels*, 5-HTP supplementation may help reduce these specific cravings* in some individuals.
Satiety signaling support means feeling appropriately satisfied after eating rather than continuing to feel hungry or experiencing persistent food thoughts despite adequate calorie consumption. Research has examined serotonin's role in signaling satiety to the brain*, suggesting that supporting adequate serotonin* may help improve satiety perception* in some individuals.
Emotional eating patterns may be influenced by serotonin status since mood and appetite are interconnected through serotonin. When mood improves with better serotonin support*, the emotional eating triggers driven by attempts to self-medicate mood through food may diminish*, potentially helping individuals better distinguish physical hunger from emotional eating urges.
Important limitations must be acknowledged—5-HTP is not a weight loss supplement and shouldn't be used primarily for that purpose. While some research has examined 5-HTP for effects on eating patterns*, results are mixed and individual responses vary greatly. Any appetite effects should be viewed as a potential secondary benefit that may help some individuals better adhere to healthy eating patterns as part of comprehensive approaches.
Professional guidance is particularly important when using supplements for appetite-related concerns, as eating issues can be complex and sometimes indicate underlying conditions requiring appropriate care. 5-HTP should be part of—not a replacement for—comprehensive approaches to healthy eating.
By potentially supporting appetite regulation and satiety through serotonin's known roles in eating behavior, ShantiMoon 5-HTP may help some individuals better manage appetite and cravings as one component of holistic wellness approaches.
Stress Resilience and Emotional Balance Support*
Serotonin's role in stress response has been extensively studied. Research has found that adequate serotonin appears to help modulate the body's stress response systems*, support emotional regulation*, and contribute to overall stress resilience*. Conversely, low serotonin has been associated with increased stress reactivity* and reduced coping capacity.
The emotional regulation aspect is particularly relevant. Serotonin appears to help maintain emotional stability* and appropriate emotional responses to situations. When levels are adequate, individuals may feel better able to handle daily stressors*, maintain perspective during challenges*, and recover more quickly from emotional upsets*.
Research on 5-HTP for stress has examined its potential to support stress management. Studies have found that 5-HTP supplementation may help support healthy stress responses* and promote emotional well-being* during stressful periods. While it doesn't eliminate stress or anxiety (which sometimes serve protective functions), it may help the body manage these responses more adaptively*.
The anxiety-serotonin connection has strong research support. Multiple studies have examined the relationship between serotonin function and anxiety, finding that supporting adequate serotonin* may help maintain emotional calm* and reduce excessive worry or tension* in some individuals. This makes 5-HTP potentially valuable for subclinical anxiety management*.
Comprehensive stress management requires multiple approaches—lifestyle modifications, stress reduction techniques, adequate sleep, exercise, social support, and professional help when needed. 5-HTP addresses the neurochemical component*, providing biochemical support that may enhance the effectiveness of other stress management strategies.
Individual variations in response to 5-HTP for stress are significant. Factors including baseline serotonin status, stress severity, concurrent health conditions, medications, and genetic factors all influence outcomes. What provides substantial benefit for one person may offer modest or no benefit for another, making individual assessment essential.
By supporting adequate serotonin levels that play crucial roles in emotional regulation and stress resilience, ShantiMoon 5-HTP may help promote better stress coping capacity and emotional balance* as part of comprehensive stress wellness approaches.
Complete Ingredient Profile
Active Ingredients:
- 5-Hydroxytryptophan (5-HTP) from Griffonia simplicifolia Seed Extract – Direct precursor to serotonin; supports serotonin synthesis in the brain*; may help promote mood balance*, support sleep quality*, help maintain healthy appetite regulation*, and contribute to stress resilience*; naturally derived from African plant seeds
Supporting Nutrients:
- Calcium (as Calcium Carbonate) – Essential mineral; supports bone health*; contributes to healthy nervous system function*; involved in neurotransmitter release*; supports muscle function*
Inactive Ingredients:
- Gelatin (capsule) – Capsule material derived from animal sources; protects ingredients and facilitates swallowing
- Magnesium Stearate – Vegetable-derived flow agent; prevents ingredients from sticking to manufacturing equipment; ensures consistent dosing
Product Specifications:
- Form: Capsules
- Count: 60 capsules per bottle
- Serving Size: 2 capsules
- Servings Per Container: 30
- Manufacturing: USA
- Capsule Type: Gelatin (not suitable for vegetarians/vegans)
Dosage Information:
- Suggested Use: Take 2 capsules once daily
- Timing: 20-30 minutes before a meal with 8oz (236ml) water
- Frequency: Once per day
- Duration: Consistent use over 4-12 weeks for optimal assessment
Important Notes:
- Not for children under 18
- Consult healthcare provider if pregnant, nursing, or have medical conditions
- Do not exceed recommended dose
- Not suitable for vegetarians (gelatin capsules)
Why Choose ShantiMoon 5-HTP?
1. Natural Serotonin Precursor Provides 5-HTP directly rather than requiring conversion from L-tryptophan, offering more efficient support for serotonin synthesis*.
2. Griffonia Simplicifolia Source Derived from natural botanical source rather than synthetic production, providing plant-based 5-HTP.
3. Comprehensive Mood Support Addresses multiple wellness areas including mood, sleep, appetite, and stress resilience through serotonin support.
4. Research-Backed Ingredient Extensive scientific literature examines 5-HTP's potential benefits* for various aspects of emotional and mental wellness*.
5. Clean, Simple Formula Straightforward ingredient list without unnecessary fillers, additives, or proprietary blends—just 5-HTP with calcium support.
6. Made in USA Domestic manufacturing ensures quality oversight and adherence to dietary supplement manufacturing standards.
7. Convenient Once-Daily Dosing Simple regimen of 2 capsules once daily makes consistent supplementation easy to maintain.
8. Affordable Wellness Support Provides one-month supply at accessible price point for those seeking natural mood and wellness support*.
9. Holistic Approach Supports the body's *natural neurotransmitter production rather than artificially manipulating brain chemistry.
10. Versatile Benefits May help with multiple wellness concerns including mood, sleep, appetite, and stress through single supplement.
How to Use for Optimal Results
Standard Dosage: Take 2 capsules once daily as a dietary supplement.
Timing Recommendations: 20-30 minutes before a meal with 8oz (236ml) glass of water, or as directed by healthcare professional.
Best Time of Day:
- Evening: Many users take in evening to support overnight serotonin-to-melatonin conversion* for sleep support
- Morning/Daytime: Others prefer earlier dosing to support mood throughout the day
- Individual experimentation: Under healthcare provider guidance, find timing that works best for your goals
With or Without Food: The suggested timing is before meals, but taking with food may reduce any potential digestive sensitivity in those with sensitive stomachs.
Consistency is Key: Daily, regular use over 4-12 weeks provides the best assessment of individual response. Benefits may emerge gradually rather than immediately.
Important Guidelines:
- Do not exceed 2 capsules daily unless directed by healthcare professional
- Not for children under 18 years of age
- Pregnant or nursing women must consult healthcare provider before use
- Those with medical conditions or taking medications should consult healthcare provider, particularly if taking antidepressants, anti-anxiety medications, or other serotonergic drugs
Usage Tips for Maximum Benefits
1. Be Patient with Results 5-HTP effects may take 4-12 weeks of consistent use to fully manifest. Don't expect immediate dramatic changes—benefits often emerge gradually.
2. Maintain Consistent Schedule Take at the same time daily to maintain steady support for serotonin synthesis* and establish a routine that's easy to remember.
3. Combine with Healthy Lifestyle 5-HTP supports—not replaces—healthy diet, adequate sleep, regular exercise, stress management, and social connections. Synergistic effects emerge when supplements complement healthy habits.
4. Consider Vitamin B6 Some practitioners suggest concurrent B6 supplementation as it's a cofactor in serotonin synthesis, though discuss with healthcare provider first to avoid excessive intake.
5. Monitor Individual Response Track mood, sleep quality, appetite, and stress levels to understand your personal response and determine if the supplement is beneficial for you.
6. Avoid Certain Combinations Never combine with prescription antidepressants (SSRIs, SNRIs, MAOIs) or other serotonergic medications without explicit healthcare provider approval—dangerous serotonin syndrome can result.
7. Stay Hydrated Adequate water intake supports overall supplement absorption and wellness, particularly when taking capsules.
8. Consider Timing Adjustments If experiencing sleep benefits but daytime drowsiness, try taking later in day. If sleep isn't improving, try earlier dosing to allow serotonin buildup during day.
9. Don't Use Long-Term Without Assessment Periodically assess (with healthcare provider) whether continued supplementation is beneficial, or if lifestyle modifications have addressed underlying issues.
10. Discontinue Before Surgery Stop taking 5-HTP at least 2 weeks before scheduled surgery as it may interact with anesthesia or other surgical medications.
Quality & Safety Information
Manufacturing Standards: ShantiMoon 5-HTP is manufactured in the USA in facilities following Good Manufacturing Practices (GMP) for dietary supplements.
Safety Guidelines:
Not for Everyone:
- Not for children under 18 years of age
- Pregnant or nursing women must consult healthcare provider
- Individuals with medical conditions should consult physician before use
Critical Drug Interactions: 5-HTP can cause dangerous interactions with:
- Antidepressants (SSRIs, SNRIs, MAOIs, tricyclics)
- Anti-anxiety medications
- Migraine medications (triptans)
- Pain medications (tramadol, meperidine)
- Carbidopa (Parkinson's medication)
- Any serotonergic drug
Serotonin Syndrome Warning: Combining 5-HTP with medications that affect serotonin can cause serotonin syndrome—a potentially life-threatening condition. Symptoms include confusion, agitation, rapid heart rate, high blood pressure, dilated pupils, muscle rigidity, and fever. Never combine without healthcare provider approval.
Potential Side Effects: Generally well-tolerated when used appropriately. Some individuals may experience:
- Nausea or digestive discomfort (often resolves with continued use or taking with food)
- Drowsiness (adjust timing if this occurs)
- In rare cases, vivid dreams or diarrhea
Pre-Surgery Precaution: Discontinue use at least 2 weeks before surgery as 5-HTP may interact with anesthesia.
Storage: Store in a cool, dry place. Do not use if safety seal is damaged or missing. Keep out of reach of children.
Who Will Benefit from This Product?
Mood Wellness Seekers: Those experiencing mild low mood or emotional flatness who want natural support for mood balance* and emotional well-being*.
Sleep Quality Improvers: Individuals with mild to moderate sleep difficulties seeking natural support for healthy sleep patterns* through the serotonin-melatonin pathway*.
Appetite Management Support: People struggling with carbohydrate cravings, emotional eating, or inadequate satiety who want to support healthy appetite regulation*.
Stress Resilience Builders: Those experiencing chronic stress or subclinical anxiety seeking natural support for emotional balance* and stress coping capacity*.
Natural Wellness Advocates: Consumers preferring natural, botanical-derived supplements that work with the body's existing pathways rather than synthetic alternatives.
Holistic Health Seekers: Individuals taking comprehensive approaches to wellness who want to address neurochemical aspects alongside lifestyle modifications.
Serotonin Support Interested: Those who've learned about serotonin's roles in mood, sleep, and appetite and want to support healthy levels*.
Tryptophan Alternative: People who've tried L-tryptophan with limited success and want to try the more direct precursor 5-HTP.
Not Candidates for Prescription: Individuals with subclinical concerns that don't meet criteria for prescription medications but still affect quality of life.
Important: Those with diagnosed mood disorders, sleep disorders, or other medical conditions should work with healthcare providers rather than relying solely on supplements.
Understanding Key Ingredients
5-Hydroxytryptophan (5-HTP)
5-HTP is an amino acid that serves as an intermediate in the biosynthesis of serotonin from L-tryptophan. When you consume 5-HTP, it crosses the blood-brain barrier and is converted to serotonin* through a one-step process involving the enzyme aromatic L-amino acid decarboxylase.
Research support for 5-HTP is substantial. A review published in Alternative Medicine Review (2008) examined clinical trials and found evidence supporting 5-HTP's potential to help with mood wellness*. Studies have examined various populations and dosages, generally finding that 50-300mg daily may provide benefits* for various individuals.
Griffonia simplicifolia is a woody climbing shrub native to West and Central Africa. Its seeds contain exceptionally high concentrations of 5-HTP (up to 20% by weight), making them the primary commercial source for 5-HTP supplements. The plant-derived origin provides naturally-occurring 5-HTP in a form the body recognizes*.
The mechanism is straightforward: 5-HTP → Serotonin → (at night) Melatonin. By providing the direct precursor, 5-HTP supplementation bypasses the rate-limiting steps* that can restrict serotonin production when starting from dietary protein alone.
Calcium
While often overlooked in discussions of mood supplements, calcium plays important roles in nervous system function* including neurotransmitter release* and nerve signal transmission*. The inclusion in this formula provides additional nutritional support for overall neurological wellness*.
Scientific References
Research on 5-HTP:
-
5-HTP and Mood:
- Birdsall TC. "5-Hydroxytryptophan: a clinically-effective serotonin precursor." Alternative Medicine Review. 1998;3(4):271-280.
- https://pubmed.ncbi.nlm.nih.gov/9727088/
-
5-HTP Overview:
- Turner EH, et al. "Serotonin a la carte: supplementation with the serotonin precursor 5-hydroxytryptophan." Pharmacology & Therapeutics. 2006;109(3):325-338.
- https://pubmed.ncbi.nlm.nih.gov/16023217/
-
5-HTP and Sleep:
- Wyatt RJ, et al. "Effects of 5-hydroxytryptophan on the sleep of normal human subjects." Electroencephalography and Clinical Neurophysiology. 1971;30(6):505-509.
- https://pubmed.ncbi.nlm.nih.gov/4106495/
-
Serotonin and Appetite:
- Halford JC, Blundell JE. "Separate systems for serotonin and leptin in appetite control." Annals of Medicine. 2000;32(3):222-232.
- https://pubmed.ncbi.nlm.nih.gov/10821329/
Note: These references are for educational purposes. Individual results vary. This product is not intended to treat disease.
Important Disclaimer
FDA/FTC Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Product Classification: ShantiMoon 5-HTP is a dietary supplement featuring 5-Hydroxytryptophan for supporting serotonin synthesis* and emotional wellness*. It is not a drug, pharmaceutical treatment, or medical therapy.
Not Medical Treatment: This product does not treat, cure, or prevent mood disorders, sleep disorders, anxiety disorders, or any disease. It supports general wellness* through providing a natural serotonin precursor. For diagnosed mental health conditions, sleep disorders, or other medical concerns, seek appropriate professional care.
Individual Results Vary: Responses to 5-HTP vary significantly based on individual factors including baseline serotonin status, genetics, diet, lifestyle, concurrent health conditions, medications, and consistency of use. The information provided is for educational purposes and should not be considered medical advice.
Critical Drug Interaction Warning: Never combine 5-HTP with antidepressants, anti-anxiety medications, or other serotonergic drugs without explicit healthcare provider approval. Dangerous serotonin syndrome can result from this combination—a potentially life-threatening condition.
Consult Healthcare Professionals: Always consult with a qualified healthcare provider before starting 5-HTP supplementation, especially if you:
- Take any medications (particularly psychiatric medications)
- Have diagnosed mood disorders, sleep disorders, or other mental health conditions
- Have any medical conditions
- Are pregnant or nursing
- Are under 18 years of age
- Are scheduled for surgery (discontinue 2 weeks prior)
Not a Substitute for Professional Care: If you have diagnosed depression, anxiety disorder, sleep disorder, or other medical conditions, this supplement does not replace proper medical treatment. Use only under healthcare provider guidance as part of comprehensive care plans.
Quality Information: While manufactured following GMP standards in the USA, statements about this product have not been evaluated by the FDA. Use only as directed.
Frequently Asked Questions
REQUIRED FDA/FTC DISCLAIMER:
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. This supplement is intended to support general wellness and should not replace a varied, balanced diet and healthy lifestyle. Always consult with a qualified healthcare professional before beginning any dietary supplement, especially if you are pregnant, nursing, have a medical condition, or are taking prescription medications.
Important Safety & Usage Warning:
Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Keep out of reach of children. Store in a cool, dry place.
Disclaimer:*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. This supplement is intended to support general wellness and should not replace a varied, balanced diet and healthy lifestyle. Always consult with a qualified healthcare professional before beginning any dietary supplement, especially if you are pregnant, nursing, have a medical condition, or are taking prescription medications.

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