Heart Health

Understanding the Four Key Challenges AgniLean Addresses*

Challenge 1: Low Energy Levels and Fatigue Throughout the Day

Many individuals struggle with maintaining consistent energy levels throughout their busy days. Factors such as demanding work schedules, insufficient nutrient intake, inadequate sleep, and the natural aging process can all contribute to feelings of tiredness and reduced vitality. When your body's natural energy production processes aren't functioning optimally, it can affect your ability to stay productive, exercise regularly, and enjoy daily activities.

How AgniLean May Help Support Your Energy Levels:*

AgniLean contains a synergistic combination of ingredients specifically chosen to support your body's natural energy production processes. L-Carnitine plays a crucial role in transporting fatty acids into the mitochondria—the powerhouses of your cells—where they can be converted into usable energy.* Our formula also includes Vitamin C and Vitamin B6, both of which contribute to normal energy-yielding metabolism and help reduce tiredness and fatigue.* Additionally, MCT Oil provides a readily available energy source that your body may utilize efficiently, potentially supporting sustained energy throughout the day when combined with proper nutrition and rest.*

Challenge 2: Suboptimal Metabolic Function and Nutrient Utilization

Your metabolism encompasses all the chemical processes that occur within your body to maintain life, including converting food into energy and building or repairing tissues. Various factors—including age, diet quality, stress levels, sleep patterns, and genetic predispositions—can influence how efficiently your metabolism functions. When metabolic processes aren't operating optimally, it may affect how your body processes nutrients, maintains healthy body composition, and supports overall wellness.

How AgniLean Supports Healthy Metabolic Function:*

AgniLean's comprehensive formula features multiple ingredients that work together to support various aspects of metabolic health. Chromium (as chromium polynicotinate) helps support the metabolism of carbohydrates and fats, which are essential macronutrients your body uses for energy and numerous physiological functions.* Choline (as choline bitartrate) is an essential nutrient that plays a crucial role in liver health and helps support the body's natural fat metabolism processes.* The formula also includes Garcinia Cambogia Fruit Extract (standardized to 50% hydroxycitric acid) and Gymnema Sylvestre Leaf Extract (25% extract), both traditional botanical ingredients that have been used to support metabolic wellness in various cultural wellness practices.*

Challenge 3: Difficulty Maintaining a Healthy Weight Management Program

Achieving and maintaining healthy body composition requires a multifaceted approach that includes balanced nutrition, regular physical activity, adequate sleep, stress management, and sometimes additional nutritional support. Many people find it challenging to stay consistent with their wellness goals, especially when they don't feel they're receiving adequate nutritional support for their efforts.

How AgniLean Complements Your Diet and Exercise Program:*

While AgniLean is not a substitute for healthy eating and regular exercise, it is formulated to complement your existing wellness efforts by providing targeted nutritional support.* The combination of MCT Oil and L-Carnitine may help support your body's natural thermogenesis—the process by which your body produces heat and energy from digesting food—when used alongside a sensible diet and exercise program.* Conjugated Linoleic Acid (CLA) and Gamma-Linolenic Acid (GLA) are essential fatty acids that have been studied for their potential role in supporting healthy body composition when combined with lifestyle modifications.* The inclusion of metabolic-supporting nutrients like Chromium and Vitamin B6 helps ensure your body has the essential cofactors needed for optimal nutrient processing and energy metabolism.*

Challenge 4: Inadequate Nutritional Support for Active Lifestyles

Individuals who maintain active lifestyles, engage in regular exercise, or have demanding physical or mental work often have increased nutritional needs. Standard diets may not always provide adequate levels of certain nutrients that support energy production, muscle function, recovery, and overall metabolic health. Without proper nutritional support, it can be more difficult to maintain performance, recover adequately, and achieve wellness goals.

How AgniLean Provides Comprehensive Nutritional Support:*

AgniLean goes beyond basic metabolic support by providing a comprehensive array of nutrients specifically chosen for individuals with active lifestyles. The formula includes Coenzyme Q10 (CoQ10), a compound naturally found in every cell of your body that plays a vital role in energy production and acts as an antioxidant.* Turmeric Root Extract (standardized to 95% curcuminoids) provides antioxidant support and has been traditionally used to support overall wellness.* The Proprietary Blend features a spectrum of amino acids including L-Tyrosine, L-Phenylalanine, and L-Methionine, which serve as building blocks for proteins and support various physiological functions. Additionally, botanical ingredients like Spirulina Powder, Kelp Extract, Cinnamon Bark Extract, and Cranberry Fruit Concentrate provide a diverse array of phytonutrients to support general well-being and nutritional adequacy.*

Understanding the Top 4 Pain Points

Pain Point #1: Limited Sun Exposure and Indoor Lifestyle

Modern indoor lifestyles dramatically reduce sunlight exposure compared to historical human experience. Office work, long commutes, indoor recreation, and climate-controlled environments mean many people spend the vast majority of waking hours indoors, with limited opportunity for the sun exposure necessary for vitamin D production. Even when outdoors, clothing covers most skin, further limiting the surface area available for vitamin D synthesis.

Geographic limitations particularly affect those living in northern latitudes (above 37 degrees North or below 37 degrees South) where winter sunlight intensity is insufficient for meaningful vitamin D production. During winter months at these latitudes, the sun's angle means UVB rays—the specific wavelength that triggers vitamin D production—don't penetrate the atmosphere adequately. This creates a "vitamin D winter" lasting approximately November through March where sunlight cannot support vitamin D production regardless of outdoor time.

Sunscreen protection, while crucial for skin cancer prevention, blocks the UVB radiation needed for vitamin D synthesis. Proper sunscreen use with SPF 30 or higher can reduce vitamin D production by 95-99%. This creates a dilemma—protecting skin from UV damage while maintaining vitamin D status—that supplementation helps resolve by providing vitamin D without requiring unprotected sun exposure.

Skin tone considerations mean individuals with darker skin require significantly more sun exposure to produce equivalent vitamin D amounts compared to those with lighter skin. Melanin acts as a natural sunscreen, protecting against UV damage but also reducing vitamin D production efficiency. Research consistently finds vitamin D insufficiency is more prevalent among people with darker skin tones living in temperate climates, where sunlight may be insufficient to overcome melanin's protective effects.

Age-related decline in vitamin D production means older adults produce 50-70% less vitamin D from the same sun exposure compared to younger adults. This reduced synthetic capacity, combined with often limited outdoor activity, increased indoor time, and medication interactions, makes older adults particularly vulnerable to vitamin D insufficiency despite adequate sun availability.

The urbanization factor means tall buildings, pollution, and urban environments block and scatter UV radiation, further reducing vitamin D production potential for city dwellers. Combined with indoor lifestyles, this urbanization effect contributes to widespread vitamin D insufficiency in modern populations.

Finding convenient vitamin D3 supplementation providing 2,000 IU daily to help maintain adequate vitamin D status* addresses the reality that modern lifestyles, geographic location, and protective behaviors make obtaining sufficient vitamin D from sunlight alone increasingly difficult for many people.

Pain Point #2: Bone Health Concerns and Calcium Absorption

Osteoporosis and osteopenia represent major public health concerns, particularly for aging populations. These conditions—characterized by reduced bone density and increased fracture risk—affect millions, with fractures causing significant morbidity, mortality, healthcare costs, and reduced quality of life. While calcium intake receives primary attention for bone health, vitamin D's essential role in calcium absorption means adequate vitamin D is equally critical for maintaining bone density*.

Calcium absorption efficiency depends directly on vitamin D status. Without adequate vitamin D, the body may absorb only 10-15% of dietary calcium; with sufficient vitamin D, absorption increases to 30-40%. This means that inadequate vitamin D essentially negates careful calcium supplementation or dietary calcium intake—the calcium simply isn't absorbed efficiently and passes through the digestive system unused.

Peak bone mass during young adulthood determines lifelong skeletal health and fracture risk in later years. Optimizing bone development during growth years and early adulthood—when bone mass accumulation is most active—requires adequate vitamin D to support calcium absorption and bone mineralization*. Inadequate vitamin D during these critical years may result in suboptimal peak bone mass, increasing lifelong osteoporosis and fracture risk.

Age-related bone loss accelerates in older adults, particularly postmenopausal women experiencing hormonal changes affecting bone metabolism. Maintaining adequate vitamin D status may help support bone density* during these higher-risk periods. Research examining vitamin D supplementation in older adults has investigated whether adequate vitamin D might help support bone health* and reduce fracture risk, with some studies suggesting potential benefits particularly when combined with adequate calcium*.

Dental health shares similar vitamin D dependence to skeletal health. Tooth development, mineralization, and the integrity of jaw bone supporting teeth all require adequate vitamin D for proper calcium utilization*. Research has examined associations between vitamin D status and dental health*, with some evidence suggesting adequate vitamin D may support oral health* and tooth integrity*.

The fracture consequence of poor bone health extends beyond pain to loss of independence, reduced mobility, increased mortality (particularly for hip fractures in elderly), and diminished quality of life. Proactive bone health support* through adequate vitamin D and calcium represents preventive investment with substantial potential long-term benefits.

Finding high-potency vitamin D3 supplementation (2,000 IU) that supports efficient calcium absorption and bone health* addresses the foundational nutritional requirement for maintaining skeletal integrity throughout life, particularly for those at higher risk due to age, sex, or limited sun exposure.

Pain Point #3: Immune System Support Needs

Seasonal immune challenges during fall and winter months coincide with declining vitamin D levels from reduced sun exposure. This observation has led to extensive research investigating potential connections between vitamin D status and immune function. While the relationship is complex and research continues, vitamin D's roles in immune regulation* have been documented in numerous studies.

Immune cell function appears influenced by vitamin D status. Vitamin D receptors exist on various immune cells including T cells, B cells, antigen-presenting cells, and others, suggesting vitamin D plays regulatory roles in immune responses*. Research has examined how vitamin D may affect both innate immunity (immediate, non-specific defenses) and adaptive immunity (learned, specific responses), with studies suggesting vitamin D helps modulate immune activity.

Inflammatory balance represents another investigated area. Appropriate immune function requires balanced responses—robust enough to address challenges but not excessive. Research suggests vitamin D may play roles in regulating inflammatory responses*, helping maintain balanced rather than excessive inflammation. Studies published in journals including Frontiers in Immunology have examined these regulatory mechanisms.

Antimicrobial peptide production is one specific mechanism by which vitamin D may support immune function*. Research has found that vitamin D influences production of cathelicidin and defensins—natural antimicrobial compounds produced by immune cells. These antimicrobial peptides represent part of the innate immune response, and adequate vitamin D may support their production*.

The winter immune challenge when colds and flu peak coincides with the period of lowest vitamin D levels in temperate climates. While correlation doesn't prove causation, this temporal relationship combined with vitamin D's documented immune roles has generated substantial research interest in whether adequate vitamin D status might support immune resilience*, particularly during seasons when vitamin D production from sunlight is minimal.

Autoimmunity research has also examined vitamin D's potential roles, given that vitamin D receptors exist on immune cells and vitamin D appears to influence immune regulation. Some research has investigated whether adequate vitamin D status might relate to balanced immune responses*, though this remains an active area of investigation with many questions remaining.

Finding vitamin D3 supplementation providing 2,000 IU daily to help maintain adequate vitamin D status that supports healthy immune system function* addresses the relationship between vitamin D and immunity, particularly relevant during months when sun exposure doesn't support adequate vitamin D production.

Complete Ingredient Profile

Active Ingredients Per Serving (1 capsule, taken twice daily):

• Calcium (as Calcium Carbonate): Provides elemental calcium to support the structural component of bones and teeth. Calcium is the most abundant mineral in the human body, with 99% stored in skeletal tissue.*

• Vitamin D3 (Cholecalciferol): The bioidentical form of Vitamin D that your skin produces from sunlight. D3 supports calcium absorption in the intestinal tract and helps maintain adequate serum calcium and phosphate concentrations for normal bone mineralization.*

• Vitamin K2 (as MK-7/Menaquinone-7): The most bioavailable and long-lasting form of Vitamin K2. MK-7 has a longer half-life than other K vitamins, providing sustained activity. It activates osteocalcin (which binds calcium to bone matrix) and matrix Gla-protein (which supports healthy calcium levels in arterial walls).*

• BioPerine® (Black Pepper Fruit Extract): A patented extract standardized to 95% piperine. Research indicates BioPerine® may enhance the bioavailability of nutrients, vitamins, and other compounds through increased absorption.*

Inactive Ingredients:

• Microcrystalline Cellulose (plant-based flow agent)
• Hypromellose (vegetable capsule)

What's NOT in Bonex: This formula contains no artificial colors, flavors, or preservatives. It is manufactured in the USA in a facility that follows Good Manufacturing Practices (GMP).

Why Choose Bonex Bone & Heart Formula?

Scientifically-Informed Formulation: Every ingredient in Bonex was selected based on its role in bone metabolism and cardiovascular support. This isn't a random collection of nutrients—it's a purposeful combination designed around how these compounds work together in human physiology.*

Optimal D3 Dosage: This formula helps maintain healthy Vitamin D levels in the blood. Bonex delivers a key nutrient amount that supports those with limited sunlight exposure, aiding overall wellness.*

Premium K2 Form: We use MK-7 (menaquinone-7) rather than cheaper forms of Vitamin K because MK-7 has superior bioavailability and remains active in your body longer, providing extended benefits from each dose.*

Enhanced Absorption Support: The inclusion of BioPerine® demonstrates our commitment to quality ingredients, which may help improve the uptake of certain nutrients. Optimal utilization is key for support.*

Convenient Twice-Daily Dosing: Rather than requiring you to take multiple products throughout the day, Bonex consolidates your bone and cardiovascular support into one streamlined supplement protocol.*

USA Manufacturing: Bonex is manufactured in the United States in a facility that adheres to Good Manufacturing Practice standards, providing assurance about production quality and consistency.*

How to Use Bonex for Optimal Results*

Standard Dosing: Take one (1) capsule twice daily as a dietary supplement. This twice-daily approach helps maintain more consistent blood levels of these nutrients throughout the day.*

Timing Recommendations: For best absorption, take each capsule 20-30 minutes before a meal with a full glass of water. Since Vitamins D3 and K2 are fat-soluble, taking them before meals that contain some dietary fat may enhance absorption.*

Consistency Matters: Nutritional supplementation works best when taken consistently over time. Make Bonex part of your daily routine by taking it at the same times each day—many users find success with a morning and evening schedule.*

Top 4 Pain Points & How Nexus Berberine Supports You

Pain Point #1: Blood Sugar Balance & Metabolic Health Concerns

Many people struggle with maintaining healthy blood sugar levels already within normal range, particularly as they age, experience stress, or face dietary challenges. Irregular blood sugar patterns can affect energy levels, mood, cravings, and overall wellness. Supporting the body's natural glucose metabolism becomes increasingly important for long-term health, yet finding effective nutritional support can be challenging.

How Nexus Supports You: Berberine is one of the most extensively researched natural compounds for supporting healthy glucose metabolism. Multiple clinical studies have demonstrated berberine's ability to help maintain blood sugar levels already within normal range through several mechanisms. Berberine activates AMPK (adenosine monophosphate-activated protein kinase), often called the "metabolic master switch," which plays a crucial role in regulating glucose and lipid metabolism. By activating AMPK, berberine helps support the body's natural insulin sensitivity, promotes healthy glucose uptake by cells, and supports the liver's ability to regulate glucose production. Our high-potency 97% berberine extract provides concentrated support for these metabolic pathways, helping your body maintain balanced blood sugar levels as part of a healthy diet and lifestyle. With consistent use alongside proper nutrition and exercise, this supplement supports your metabolic health and helps you maintain steady energy throughout the day.*

Pain Point #2: Cardiovascular Health & Cholesterol Management

Heart health is a major concern for millions of people, particularly those with family history or age-related cardiovascular considerations. Maintaining healthy cholesterol levels—including LDL, HDL, and triglycerides—is crucial for cardiovascular wellness. Many people seek natural ways to support heart health and maintain cholesterol levels already within normal range without immediately resorting to pharmaceutical interventions.

How Nexus Supports You: Research has shown berberine's impressive potential for supporting cardiovascular health through multiple pathways. Berberine helps support healthy cholesterol levels already within normal range by influencing cholesterol metabolism in the liver and promoting healthy lipid profiles. Studies indicate berberine may help maintain healthy LDL cholesterol, support optimal HDL cholesterol, and promote balanced triglyceride levels. Additionally, berberine supports healthy endothelial function (the inner lining of blood vessels), which is crucial for cardiovascular health. The compound's antioxidant properties help protect against oxidative stress that can affect cardiovascular tissues. By activating AMPK, berberine also supports healthy fat metabolism and may help reduce fat accumulation in the liver. Our cardiovascular support berberine formula provides comprehensive nutritional support for heart health, helping you maintain healthy cholesterol balance and supporting your cardiovascular system's optimal function as part of a heart-healthy lifestyle including proper diet and regular physical activity.*

Pain Point #3: Weight Management Challenges & Metabolic Rate

Despite efforts with diet and exercise, many people struggle with weight management, metabolic slowdown, and difficulty maintaining healthy body composition. Factors including age, hormones, stress, sleep quality, and metabolic efficiency all impact weight management success. Supporting the body's natural metabolic rate and fat-burning capacity can make a significant difference in weight management efforts.

How Nexus Supports You: While not a magic weight-loss pill, berberine has been studied for its potential to support healthy weight management when combined with proper diet and exercise. Through AMPK activation, berberine helps support the body's fat-burning processes and may help promote healthy metabolic rate. Research suggests berberine may support healthy body composition by influencing how the body stores and utilizes fat, supporting healthy adipose tissue function, and promoting balanced energy metabolism. Berberine may also help support healthy appetite regulation and promote feelings of satiety when combined with balanced meals. Additionally, by supporting healthy blood sugar balance, berberine helps reduce energy crashes and cravings that can derail healthy eating plans. Our metabolic wellness berberine supplement provides nutritional support for your weight management journey, helping optimize your body's natural fat metabolism when used as part of a comprehensive program including calorie-conscious nutrition and regular physical activity. Remember: sustainable weight management requires lifestyle changes—berberine is a supportive tool, not a replacement for healthy habits.*

Pain Point #4: Gut Health & Microbiome Balance

Digestive health and microbiome balance are increasingly recognized as foundational to overall wellness, affecting everything from immune function to mood, metabolism, and inflammation. Many people experience gut imbalances, occasional digestive discomfort, or seek to support their intestinal health. The gut microbiome plays crucial roles in nutrient absorption, immune function, and even metabolic health.

How Nexus Supports You: Emerging research highlights berberine's potential to support healthy gut microbiome balance. Berberine exhibits antimicrobial properties that may help maintain healthy bacterial balance in the digestive tract, supporting beneficial bacteria while helping control overgrowth of less desirable microorganisms. Studies suggest berberine may help support the integrity of the intestinal barrier, promote healthy gut lining function, and support balanced inflammatory responses in the digestive tract. The gut-metabolic connection means that supporting gut health through berberine may also contribute to better metabolic outcomes, as the microbiome influences glucose metabolism, fat storage, and appetite regulation. Additionally, berberine's support for healthy bile flow contributes to optimal fat digestion and nutrient absorption. By supporting a balanced gut environment, our berberine supplement contributes to foundational wellness that extends beyond just digestive health, influencing overall metabolic function, immune support, and vitality.*

Understanding the Top 4 Pain Points

Pain Point #1: Difficulty Falling Asleep (Sleep Onset Issues)

Trouble falling asleep is one of the most common sleep complaints affecting millions of adults worldwide. Lying in bed with a racing mind, unable to relax into sleep despite exhaustion, is a frustrating experience that can create anxiety around bedtime itself. Sleep onset difficulties can stem from numerous factors including stress, overstimulation from screens, irregular schedules, caffeine consumption, or simply an overactive mind.

The modern lifestyle presents unique challenges to natural sleep onset. Blue light exposure from devices, consumption of stimulating content before bed, work-related stress, and the "always-on" culture of constant connectivity can all interfere with the body's natural transition from wakefulness to sleep. Many people find themselves mentally alert at times when their bodies are physically exhausted.

Delayed sleep onset creates a cascading effect on overall sleep quality and next-day functioning. When you spend an hour or more trying to fall asleep, you lose valuable sleep time even if you eventually achieve rest. This can result in insufficient total sleep duration, leading to daytime fatigue, reduced cognitive performance, mood disturbances, and increased reliance on caffeine to compensate.

The sleep-wake cycle (circadian rhythm) depends on various internal and external cues to function optimally. When this cycle is disrupted—by irregular schedules, jet lag, shift work, or lifestyle factors—the body may not naturally produce sleep-inducing compounds at appropriate times. This misalignment between when you want to sleep and when your body is ready to sleep creates frustrating sleep onset delays.

Many individuals seeking sleep support* specifically struggle with the transition period between wakefulness and sleep. They need help signaling to their body that it's time to rest, quieting mental activity, and initiating the physiological changes that accompany sleep onset. Finding natural approaches to support this transition* becomes a priority for those tired of lying awake night after night.

Pain Point #2: Poor Sleep Quality and Lack of Deep, Restorative Rest

Even individuals who fall asleep relatively easily may struggle with sleep quality issues—waking frequently during the night, experiencing restless or shallow sleep, or waking up feeling unrefreshed despite adequate time in bed. Quality matters as much as quantity when it comes to sleep's restorative benefits*.

Sleep architecture involves multiple sleep stages, each serving important functions. Light sleep stages provide transition periods, while deep sleep (slow-wave sleep) supports physical restoration, immune function, and metabolic health*. REM (rapid eye movement) sleep is particularly important for cognitive functions including memory consolidation, emotional processing, and learning*. When sleep is fragmented or doesn't progress through these stages appropriately, its restorative value diminishes significantly.

Sleep fragmentation—frequent brief awakenings during the night—prevents the sustained periods of deep and REM sleep necessary for optimal restoration*. Even if individuals don't fully remember these awakenings, they can significantly impact sleep quality. People may spend eight hours in bed but wake feeling as though they've barely rested, experiencing daytime fatigue, difficulty concentrating, and reduced stress resilience.

Multiple factors can compromise sleep quality including environmental disruptions (noise, light, temperature), physical discomfort, stress, anxiety, dietary factors, and age-related changes in sleep patterns. As we age, sleep naturally becomes lighter and more easily disrupted, making sleep quality support* increasingly important for older adults.

The consequences of chronically poor sleep quality extend far beyond feeling tired. Research has associated inadequate quality sleep with numerous health implications including compromised immune function, metabolic changes, cognitive difficulties, mood disturbances, and reduced quality of life. Supporting consistent, high-quality sleep* becomes essential for maintaining overall wellness*.

Pain Point #3: Irregular Sleep Schedules and Circadian Rhythm Disruption

Shift workers, frequent travelers, and individuals with inconsistent schedules face unique sleep challenges. The body's internal clock (circadian rhythm) thrives on consistency, yet modern life often demands flexibility that conflicts with this biological preference. When required to sleep at different times or across time zones, many struggle to achieve restful sleep.

Shift work affects millions of workers in healthcare, transportation, manufacturing, hospitality, and emergency services. Working nights or rotating shifts requires sleeping during times when the body's circadian rhythm promotes wakefulness, while remaining alert during times when the body naturally wants to sleep. This fundamental misalignment can make quality rest extremely difficult to achieve.

Jet lag creates similar challenges for travelers crossing multiple time zones. The body's internal clock remains synchronized to the home time zone for several days, creating a mismatch between local time and internal biological time. This results in difficulty sleeping at appropriate times in the new location, along with daytime fatigue and cognitive sluggishness.

Even without shift work or travel, many people maintain irregular sleep schedules—going to bed at significantly different times on weekdays versus weekends, or varying schedules based on social activities. This "social jet lag" can disrupt circadian rhythms and compromise sleep quality*, making it difficult for the body to establish consistent sleep-wake patterns.

Circadian rhythm disruption affects more than just sleep. These 24-hour biological cycles regulate hormone production, metabolism, body temperature, and numerous other physiological processes. When these rhythms are consistently disrupted, it can affect overall health and well-being*. Supporting the body's natural sleep-wake cycle* becomes particularly important for individuals whose lifestyles challenge circadian consistency.

Why You Need Resveratrol: Top Reasons to Consider This Supplement

Environmental factors and the natural aging process may influence cellular health. Resveratrol is known to provide antioxidant support that may benefit the cells.*

Here's why thousands of wellness-focused individuals are adding resveratrol supplements to their daily regimen:

Oxidative Stress Management: Free radicals are unstable molecules produced during normal metabolism and environmental exposure. Free radicals are produced through normal metabolism over time. Resveratrol's antioxidant properties help balance free radicals, supporting healthy cells throughout your body.*

Cardiovascular Wellness Goals: Many individuals seek natural ways to support heart health as part of a comprehensive wellness approach. Resveratrol has been studied for its potential role in supporting healthy cardiovascular function when combined with regular exercise and a heart-healthy diet.*

Cognitive Function Support: Mental clarity and cognitive performance are priorities at every age. The antioxidant properties of resveratrol may help support normal cognitive function and mental sharpness as part of a brain-healthy lifestyle.*

Healthy Aging Support: The aging process is natural, but supporting your body's cellular health may help you maintain vitality and wellness as you age. Resveratrol has been researched for its potential role in supporting healthy aging processes at the cellular level.*

Metabolic Function Support: Maintaining a healthy metabolism is essential for overall wellness. When combined with a balanced diet and regular physical activity, resveratrol may help support general metabolic processes.*

Top 4 Pain Points & How This Supplement May Help

Pain Point #1: Inadequate Omega-3 Intake from Diet Alone

Insufficient omega-3 fatty acid intake is remarkably common in modern Western diets, which tend to be disproportionately high in omega-6 fatty acids (from vegetable oils, processed foods, and grain-fed animal products) while lacking adequate omega-3s from marine sources. The typical American diet provides only about 100-200mg of combined EPA and DHA daily—far below the 250-500mg minimum recommended by most health organizations, and significantly less than the 1,000mg or more suggested for cardiovascular support. Multiple factors contribute to this deficiency: limited consumption of fatty fish (surveys show most Americans eat fish less than once per week), concerns about mercury and environmental contaminants in fish, dislike of fish taste or smell, dietary restrictions (vegetarian/vegan diets), food allergies to seafood, cost of high-quality fresh fish, limited access in certain geographic areas, and simply not knowing which foods contain omega-3s or how much to consume. This widespread omega-3 insufficiency is concerning because EPA and DHA are integral components of cell membranes throughout the body, particularly in the brain, heart, and eyes, where they support optimal structure and function. Without adequate intake, the body must use less optimal fatty acids in these crucial roles, potentially compromising cellular function and overall health. The modern dietary shift toward processed foods and away from traditional omega-3-rich foods has created a significant nutritional gap that affects millions of people's health and wellness potential.

How Omneva Omega-3 Supports You:

This convenient omega-3 supplement is specifically designed to help bridge the dietary gap between typical omega-3 intake and optimal levels for supporting health.* Each serving provides 180mg of EPA and 120mg of DHA (300mg combined) from quality fish oil concentrate, delivering a meaningful dose of these essential fatty acids in just one or two easy-to-swallow softgels daily.* This targeted amount helps you meet baseline omega-3 needs without requiring you to drastically change your diet or consume fish multiple times per week—though omega-3 supplementation works best as part of an overall healthy dietary pattern that includes diverse nutrient sources.* EPA (Eicosapentaenoic Acid) is a 20-carbon omega-3 fatty acid that's particularly recognized for its role in supporting cardiovascular wellness, helping to maintain healthy triglyceride levels already within normal range, and contributing to normal inflammatory response regulation throughout the body.* Research has investigated EPA's potential to support healthy lipid metabolism and cardiovascular function through various mechanisms.* DHA (Docosahexaenoic Acid) is a 22-carbon omega-3 fatty acid that's highly concentrated in the brain and retina, where it serves as a structural component of cell membranes and plays crucial roles in supporting cognitive function, memory, learning, mood regulation, and visual acuity.* DHA comprises approximately 40% of the polyunsaturated fatty acids in the brain and 60% in the retina, highlighting its importance for neurological and visual health throughout the lifespan—from prenatal development through aging.* The fish oil concentrate used in this formula provides EPA and DHA in their natural triglyceride form, which research suggests is well-absorbed and efficiently incorporated into body tissues.* Vitamin E (as mixed tocopherols) is included as a natural antioxidant preservative that helps protect the delicate omega-3 fatty acids from oxidation, ensuring product freshness, potency, and quality.* The softgel delivery system (gelatin, glycerin, and water) encapsulates the fish oil in an easy-to-swallow form that protects the oil from air exposure while making supplementation convenient and travel-friendly.* By providing a consistent, reliable source of EPA and DHA, this supplement helps ensure your body has adequate omega-3 fatty acids to support optimal cellular function, cardiovascular wellness, cognitive health, and overall vitality—regardless of day-to-day dietary variations or challenges in consuming sufficient fatty fish.*

Pain Point #2: Cardiovascular Health Concerns and Lipid Balance

Cardiovascular wellness is a primary health concern for millions of adults, particularly as they age or face risk factors including family history, sedentary lifestyle, poor dietary habits, chronic stress, smoking, excess weight, or simply the natural changes that occur with aging. Maintaining healthy cardiovascular function requires supporting multiple interconnected systems including heart rhythm, blood vessel health, healthy circulation, appropriate blood pressure already within normal range, and proper lipid metabolism—particularly maintaining healthy triglyceride and cholesterol levels within normal ranges. Triglycerides are a type of fat found in blood that, when elevated beyond healthy levels, can impact cardiovascular wellness. Many people struggle to maintain optimal triglyceride levels through lifestyle measures alone, particularly when dealing with dietary patterns high in refined carbohydrates, sugars, and unhealthy fats. Similarly, supporting a healthy balance of HDL ("good") cholesterol and LDL cholesterol ratios is important for cardiovascular health. The challenge is that cardiovascular health is influenced by numerous factors—genetics, diet, exercise, stress, sleep, and more—making it difficult to address through single interventions. Conventional dietary advice to "eat more fish" is difficult for many to follow consistently due to cost, availability, preparation time, taste preferences, or mercury concerns. Without adequate omega-3 intake, individuals miss out on the cardiovascular-supporting properties that these essential fatty acids provide through their various mechanisms of action in the cardiovascular system.

How Omneva Omega-3 Supports You:

This cardiovascular-supporting omega-3 formula is designed to help promote heart and circulatory system wellness through the well-researched benefits of EPA and DHA.* EPA (180mg per serving) has been extensively studied for its potential role in supporting cardiovascular health, particularly in helping to maintain healthy triglyceride levels already within the normal range.* Research suggests EPA may support healthy lipid metabolism through multiple mechanisms, including potential effects on hepatic (liver) triglyceride synthesis and very-low-density lipoprotein (VLDL) production and secretion.* By helping to support healthy fat metabolism in the liver, EPA may contribute to maintaining balanced blood lipid profiles.* Numerous clinical studies and meta-analyses have investigated omega-3 fatty acids' potential to support cardiovascular wellness, with particular interest in EPA's role.* DHA (120mg per serving) complements EPA's cardiovascular benefits and contributes to supporting normal heart function and healthy blood pressure already within the normal range.* The combination of EPA and DHA provides comprehensive omega-3 support for the cardiovascular system, helping to maintain the structural integrity of heart cell membranes, support healthy electrical signaling for normal heart rhythm, promote healthy endothelial function (the inner lining of blood vessels), and contribute to normal inflammatory response regulation throughout the cardiovascular system.* The 2:3 ratio of EPA to DHA (180mg:120mg) in this formula reflects a balanced approach that provides meaningful amounts of both fatty acids, each contributing their specific benefits.* The fish oil source ensures bioavailable omega-3s in natural triglyceride form that the body recognizes and can efficiently utilize.* Vitamin E inclusion not only preserves product quality but also provides additional antioxidant support that complements omega-3s' cardiovascular benefits, as oxidative stress is a factor in cardiovascular health that antioxidants help address.* By providing consistent daily omega-3 supplementation, this formula helps support the nutritional foundation for cardiovascular wellness—complementing (not replacing) a heart-healthy lifestyle that includes balanced nutrition, regular physical activity, stress management, adequate sleep, and regular check-ups with healthcare providers.* The convenient softgel format makes it easy to maintain consistent supplementation, which is key for experiencing omega-3s' cumulative benefits that build over time with regular intake.*

Pain Point #3: Cognitive Function, Memory, and Brain Health Challenges

Cognitive health and optimal brain function are increasingly important concerns, particularly as populations age and awareness grows about the importance of supporting brain health throughout the lifespan. The brain is approximately 60% fat by dry weight, with DHA comprising a significant portion of those fatty acids, highlighting the critical importance of omega-3 nutrition for cognitive wellness. Many people experience occasional mental fog, difficulty concentrating, memory lapses, slower processing speed, or concerns about maintaining cognitive sharpness as they age. These experiences can impact work performance, learning capacity, daily task completion, and overall quality of life. Multiple factors affect brain health including genetics, cardiovascular health (which influences brain blood flow), oxidative stress, inflammation, nutritional status, physical activity, mental stimulation, sleep quality, stress levels, and environmental exposures. DHA is particularly crucial for brain structure and function—it's preferentially incorporated into neuronal cell membranes where it influences membrane fluidity, receptor function, neurotransmitter signaling, and neuroplasticity (the brain's ability to form new connections). Insufficient DHA intake may compromise optimal cognitive function, particularly as we age and face natural cognitive changes. The challenge is that brain health requires long-term, consistent nutritional support—sporadic fish consumption or inconsistent supplementation doesn't provide the sustained DHA levels needed for optimal neurological support. Many people are unaware that omega-3s, particularly DHA, play such crucial roles in cognitive health, or they underestimate how much omega-3 supplementation may help support mental clarity, focus, memory, and overall brain wellness.

How Omneva Omega-3 Supports You:

This brain-supporting omega-3 formula provides targeted nutritional support for cognitive function and neurological wellness through its meaningful DHA content (120mg per serving).* DHA (Docosahexaenoic Acid) is the predominant structural omega-3 fatty acid in the brain, particularly concentrated in the cerebral cortex (responsible for memory, language, creativity, judgment, emotion, and attention), hippocampus (critical for memory formation and learning), and other brain regions essential for cognitive function.* DHA helps maintain the structural integrity and optimal fluidity of neuronal cell membranes, which is crucial for efficient neurotransmitter signaling, ion channel function, and cellular communication throughout the nervous system.* Research has investigated DHA's potential role in supporting memory, learning capacity, attention span, processing speed, and overall cognitive performance across various age groups.* Studies suggest DHA may help support the production of neuroprotective compounds, promote healthy brain-derived neurotrophic factor (BDNF) levels (important for neuroplasticity and neuronal survival), and contribute to maintaining healthy brain structure and volume as we age.* EPA (180mg per serving) complements DHA's cognitive benefits by helping to support healthy inflammatory response regulation in the brain and throughout the body.* Emerging research suggests EPA may also play roles in supporting mood regulation and emotional wellness through its various mechanisms of action in the brain.* The combination of EPA and DHA provides comprehensive omega-3 support for the nervous system, as both fatty acids contribute to optimal neurological function through complementary pathways.* By providing consistent, daily omega-3 supplementation, this formula helps ensure the brain has adequate DHA and EPA to support optimal cognitive function, mental clarity, focus, memory, and overall neurological wellness.* The benefits of omega-3s for brain health are cumulative—building over time with consistent intake rather than providing immediate effects—making daily supplementation important for long-term cognitive support.* The convenient softgel format makes it easy to maintain the consistent intake pattern needed for supporting cognitive health, and the inclusion of Vitamin E helps protect these delicate fatty acids from oxidation, ensuring they reach your brain in optimal condition.* Whether you're a student seeking to support learning and memory, a professional wanting to maintain mental sharpness and productivity, or an older adult interested in supporting cognitive health during aging, this omega-3 formula provides the nutritional foundation for brain wellness at any age.*

Pain Point #4: Vision Health and Age-Related Eye Concerns

Visual health and eye function become increasingly important considerations as people age or spend extensive time in visually demanding environments, particularly with the modern prevalence of digital screens, artificial lighting, and environmental stressors that challenge eye health. DHA is the predominant structural fatty acid in the retina, comprising approximately 50-60% of the total fatty acids in photoreceptor outer segments—the specialized structures in rod and cone cells that detect light and enable vision. Despite its critical importance for eye structure and function, many people consume insufficient DHA to optimally support visual wellness. Common eye concerns include age-related changes in visual acuity, difficulty with night vision, dry eyes, eye strain from extended screen time, light sensitivity, and general worries about maintaining healthy vision throughout the lifespan. The retina has unique nutritional requirements due to its high metabolic activity, constant light exposure, high oxygen consumption, and abundance of polyunsaturated fatty acids that require antioxidant protection. Without adequate omega-3 support, particularly DHA, the eyes may not have optimal nutritional resources to maintain healthy structure and function, support tear production and eye surface health, or defend against oxidative stress from light exposure. Many eye health supplements focus solely on antioxidants (lutein, zeaxanthin, vitamins) while overlooking the foundational importance of omega-3 fatty acids, particularly DHA, for retinal structure and function. Additionally, the connection between omega-3 intake and eye health is less widely known than omega-3s' cardiovascular or anti-inflammatory properties, so people may not realize that fish oil supplementation can support visual wellness.

How Omneva Omega-3 Supports You:

This vision-supporting omega-3 formula provides essential nutritional support for eye health and visual function through its DHA content (120mg per serving), which is crucial for maintaining healthy retinal structure and optimal visual processing.* DHA is highly concentrated in the retina, particularly in the photoreceptor cells (rods and cones) where it comprises a major portion of the cell membranes.* These membranes need optimal fluidity and proper fatty acid composition to function correctly, as they're involved in the phototransduction cascade—the process by which light signals are converted into electrical signals that the brain interprets as vision.* Research has investigated DHA's essential role in supporting retinal development (particularly important during pregnancy and infancy for the developing visual system), maintaining adult visual function, and potentially supporting healthy visual aging.* Studies suggest adequate DHA status may help support various aspects of visual function including visual acuity (sharpness of vision), contrast sensitivity, color perception, and night vision.* DHA also helps support the health of retinal pigment epithelium (RPE) cells, which play crucial roles in supporting photoreceptor health, recycling visual pigments, and protecting the retina from oxidative damage.* The omega-3 fatty acids in this formula may also help support healthy tear production and eye surface health, which is increasingly important given the prevalence of dry eye concerns associated with aging, environmental factors, and extended screen time that reduces blink rate.* EPA (180mg per serving) contributes to eye health by helping to support healthy inflammatory response regulation and by promoting healthy blood flow to ocular tissues, ensuring adequate nutrient delivery and waste removal.* The Vitamin E included in this formula provides additional benefit for eye health as an antioxidant that helps protect the delicate fatty acids in the retina from oxidative damage caused by constant light exposure, which generates reactive oxygen species.* The retina is particularly vulnerable to oxidative stress due to its high metabolic rate, abundant polyunsaturated fatty acids, and constant light exposure, making antioxidant protection crucial.* By providing consistent omega-3 support, particularly DHA, this supplement helps ensure your eyes have the nutritional foundation they need to support optimal visual function, maintain healthy retinal structure, and promote overall eye wellness throughout your life. Whether you're concerned about supporting your vision as you age, wanting to support eye health during extensive screen time, or simply seeking to maintain optimal visual function, this omega-3 formula provides valuable nutritional support for one of your most precious senses.

Top 4 Pain Points & How This Supplement May Help

Pain Point #1: Declining Exercise Performance and Training Plateaus

Exercise performance limitations and training plateaus frustrate countless fitness enthusiasts and athletes who dedicate significant time and effort to their workouts but struggle to see continued progress or improvements in strength, endurance, power output, and overall athletic capacity. Multiple factors contribute to exercise performance challenges including inadequate nutrient delivery to working muscles during training, insufficient oxygen supply to muscle tissue during intense exercise, limited blood flow restricting the removal of metabolic waste products like lactate that contribute to fatigue, poor muscle pump and vascularity during resistance training, reduced exercise capacity and endurance during cardiovascular activities, longer recovery times between training sessions, difficulty achieving progressive overload in strength training programs, and the natural decline in nitric oxide production that occurs with aging—typically beginning in the 20s and 30s and accelerating thereafter. As nitric oxide levels decline, blood vessels may not dilate as efficiently, potentially limiting the increased blood flow that working muscles require during exercise to receive oxygen, glucose, amino acids, and other nutrients while removing carbon dioxide, lactate, and other metabolic byproducts. This can manifest as hitting a wall during workouts, feeling like muscles aren't getting a good pump, experiencing premature fatigue, struggling to increase weights or reps despite consistent training, or feeling like workouts that were once manageable now feel significantly more challenging. Many people don't realize that circulation and blood flow play such critical roles in exercise performance, or that supporting nitric oxide production through targeted amino acid supplementation may help address these training challenges.

How Oxivra Nitric Oxide Supports You:

This exercise performance formula is specifically designed to help support your body's natural nitric oxide production through three synergistic amino acid precursors that work together to promote healthy blood flow and circulation during physical activity.* L-Arginine Alpha-Ketoglutarate (AAKG) is a compound combining the amino acid L-arginine with alpha-ketoglutarate, creating a form that's popular among athletes and bodybuilders for its potential to support exercise performance.* L-arginine serves as a direct precursor to nitric oxide—your body converts arginine into nitric oxide through enzymes called nitric oxide synthases (NOS).* By providing supplemental arginine, particularly in the alpha-ketoglutarate form which some research suggests may have enhanced bioavailability, this formula helps ensure your body has adequate substrate to support nitric oxide production, particularly during times of increased demand like exercise.* The alpha-ketoglutarate component is also involved in the Krebs cycle (cellular energy production), potentially providing additional benefits for exercise metabolism.* L-Arginine Hydrochloride provides additional arginine in a highly stable, water-soluble form that's well-absorbed and contributes to the total arginine pool available for nitric oxide synthesis.* Research has investigated arginine supplementation's potential to support exercise performance, endurance, strength gains, and recovery through its role in promoting vasodilation and increased blood flow to working muscles.* L-Citrulline DL-Malate is perhaps the most important ingredient in this formula—citrulline is another amino acid that's actually converted into arginine in the body, but with some unique advantages.* Studies suggest that citrulline supplementation may increase blood arginine levels more effectively than arginine supplementation alone because citrulline bypasses first-pass metabolism in the liver, gets absorbed more efficiently, and provides sustained arginine elevation over time.* The malate component (malic acid) is involved in energy production and may help support exercise performance through its role in the Krebs cycle and ATP production.* Research has investigated citrulline malate's potential to support exercise performance, reduce muscle fatigue, improve training volume, and enhance recovery.* When these three amino acids work together—providing both direct arginine and the citrulline that converts to arginine—they create a comprehensive approach to supporting nitric oxide production and the healthy vasodilation that can help increase blood flow to working muscles during exercise.* This enhanced blood flow may help deliver more oxygen, glucose, amino acids, creatine, and other nutrients to muscle tissue while facilitating the removal of metabolic waste products, potentially supporting improved exercise performance, better muscle pump, enhanced endurance, and more effective training sessions. The vegetable capsule form provides convenient dosing that can be timed around workouts—many people take nitric oxide supplements 30-60 minutes before training to support blood flow during exercise. With consistent use as part of a comprehensive training program that includes progressive overload, proper nutrition, adequate recovery, and appropriate training volume and intensity, this formula helps provide the nutritional support your cardiovascular and muscular systems need to perform optimally during challenging workouts.

Resveratrol

Resveratrol is a polyphenolic compound found in grape skins, red wine, berries, and plants like Japanese Knotweed. It has been the subject of extensive scientific investigation.

Cardiovascular Health: Numerous studies have explored Resveratrol's potential role in supporting cardiovascular health. Research suggests it may help support healthy blood vessel function and cardiovascular wellness through various mechanisms.*

Neuroprotective Properties: Resveratrol has been studied for its potential to support cognitive function and brain health. Some research suggests it may help support healthy neuronal function as part of the aging process.*

Sirtuin Activation: Like NAD+, Resveratrol has been shown to interact with sirtuins, a family of proteins involved in cellular regulation and stress responses. This shared pathway is one reason Resveratrol and NAD+ are often combined in formulations.*

Cellular Health Support: Resveratrol's antioxidant properties and its effects on cellular signaling pathways have made it a popular compound for those interested in supporting healthy aging at the cellular level.*

Research Reference: Smoliga JM, et al. "Resveratrol and health--a comprehensive review of human clinical trials." Molecular Nutrition & Food Research. 2011;55(8):1129-1141. https://pubmed.ncbi.nlm.nih.gov/21688389/ Summary: This comprehensive review analyzes human clinical trials examining Resveratrol supplementation, discussing outcomes related to cardiovascular health, metabolic function, and other health parameters.

Research Reference: Witte AV, et al. "Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults." Journal of Neuroscience. 2014;34(23):7862-7870. https://pubmed.ncbi.nlm.nih.gov/24899709/ Summary: This human study investigated the effects of Resveratrol supplementation on cognitive performance and brain function in older adults, showing potential benefits for memory and brain health markers.

Complete Ingredient Profile

Active Ingredient:

• Coenzyme Q-10 (Ubiquinone) - 100mg per capsule

Other Ingredients:

• Hypromellose (vegetable capsule) - A plant-derived capsule material that makes this supplement suitable for vegetarians
• Rice Flour - Used as a natural flowing agent to ensure consistent dosing