Bonex Vitamin D3, K2 MK-7 & Calcium Supplement | Promotes Healthy Bone Density and Cardiovascular Wellness | 60 Capsules*
$68.95 USD
Unit price perIn stock
Estimated delivery between December 16 and December 20.
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Additional Information
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Manufacturer Country
USA
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Product Amount
60 caps
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Gross Weight
0.25lb (113g)
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Suggested Use
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Take one (1) capsule twice a day as a dietary supplement. For best results, take 2030 min before a meal or as directed by your healthcare professional.
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Caution
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Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
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Warning
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Keep out of reach of children. Do not use if the safety seal is damaged or missing. Store in a cool, dry place.
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Benefits of Bonex Vitamin D3, K2 MK-7 & Calcium Supplement | Promotes Healthy Bone Density and Cardiovascular Wellness | 60 Capsules*
Discover the key benefits that make our product stand out
Support Strong Bone Health
Enhance Calcium Absorption
Maintain Bone Density
Support Overall Skeletal Health
About Bonex Vitamin D3, K2 MK-7 & Calcium Supplement | Promotes Healthy Bone Density and Cardiovascular Wellness | 60 Capsules*
Bonex Bone & Heart Formula: Premium D3, K2 MK-7 & Calcium Support for Strong Bones and Cardiovascular Wellness*
Building and maintaining strong bones doesn't happen by accident. Your skeletal system requires specific nutrients working together in harmony to support bone density, calcium absorption, and overall structural integrity.* Bonex Bone & Heart Formula delivers a scientifically-informed blend of Vitamin D3, Vitamin K2 as MK-7, and Calcium with enhanced absorption technology to help you maintain the foundation of your body's framework.*
This isn't just another calcium supplement. Bonex represents a comprehensive approach to skeletal and cardiovascular support, combining three essential nutrients that work synergistically in your body.* Each capsule delivers targeted nutritional support designed to help maintain bone strength, promote proper calcium utilization, and contribute to cardiovascular function.*
Why Your Body Needs This Nutritional Support
Many adults face nutritional gaps that may affect bone health and cardiovascular wellness. Here's why targeted supplementation with Vitamin D3, K2, and Calcium may benefit you:
Limited Sun Exposure: Modern indoor lifestyles mean many people don't synthesize adequate Vitamin D3 naturally. This "sunshine vitamin" plays a crucial role in calcium absorption, and without sufficient levels, your body may struggle to utilize dietary calcium effectively.*
Dietary Insufficiency: The typical Western diet often lacks sufficient Vitamin K2 (MK-7), which is primarily found in fermented foods like natto. This nutrient helps support proper calcium distribution in the body, directing it toward bones rather than soft tissues.*
Age-Related Changes: As we age, our bodies may become less efficient at absorbing calcium and producing Vitamin D3 from sunlight. Supporting these processes through supplementation may help maintain bone density and cardiovascular function throughout the aging process.*
Calcium Paradox Concerns: Taking calcium alone without the cofactors that direct its proper utilization may not provide optimal benefits. Bonex addresses this by combining calcium with both D3 for absorption and K2 for proper distribution.*
Cardiovascular Wellness: Emerging research suggests that Vitamin K2 may play a role in supporting cardiovascular health by promoting healthy calcium metabolism in blood vessels.* When combined with adequate Vitamin D3, this duo supports both skeletal and cardiovascular systems.*
How Bonex Supports Your Bone Health and Cardiovascular Goals*
Enhanced Calcium Absorption: Vitamin D3 in Bonex helps your intestines absorb calcium more efficiently from your diet and supplements.* Without adequate D3, much of the calcium you consume may pass through your system unutilized. By providing 125 mcg (5000 IU) of cholecalciferol per serving, Bonex supports optimal calcium uptake.*
Directed Calcium Utilization: Vitamin K2 as MK-7 activates specific proteins (matrix Gla-protein and osteocalcin) that help direct calcium to your bones and teeth where it's needed, while supporting healthy calcium levels in soft tissues.* This targeted action represents one of K2's most valuable contributions to bone and cardiovascular health.*
Structural Bone Support: Calcium carbonate provides elemental calcium, the primary mineral component of bone tissue. When combined with D3 and K2, this calcium is better absorbed and more effectively incorporated into bone matrix, supporting bone density and skeletal strength.*
Bioavailability Enhancement: BioPerine® black pepper extract increases the bioavailability of the fat-soluble vitamins in this formula, helping ensure your body can access and utilize these important nutrients.* This patented ingredient has been shown in studies to enhance nutrient absorption by up to 30-60% for certain compounds.
Synergistic Triple Action: The three-nutrient system in Bonex works like a well-coordinated team—D3 facilitates calcium entry into your bloodstream, K2 activates proteins that direct where calcium goes, and calcium provides the raw material your bones need. This coordinated approach offers more comprehensive support than any single nutrient alone.*
Complete Ingredient Profile
Active Ingredients Per Serving (1 capsule, taken twice daily):
- Calcium (as Calcium Carbonate): Provides elemental calcium to support the structural component of bones and teeth. Calcium is the most abundant mineral in the human body, with 99% stored in skeletal tissue.*
- Vitamin D3 (Cholecalciferol): The bioidentical form of Vitamin D that your skin produces from sunlight. D3 supports calcium absorption in the intestinal tract and helps maintain adequate serum calcium and phosphate concentrations for normal bone mineralization.*
- Vitamin K2 (as MK-7/Menaquinone-7): The most bioavailable and long-lasting form of Vitamin K2. MK-7 has a longer half-life than other K vitamins, providing sustained activity. It activates osteocalcin (which binds calcium to bone matrix) and matrix Gla-protein (which supports healthy calcium levels in arterial walls).*
- BioPerine® (Black Pepper Fruit Extract): A patented extract standardized to 95% piperine. Research indicates BioPerine® may enhance the bioavailability of nutrients, vitamins, and other compounds through increased absorption.*
Inactive Ingredients:
- Microcrystalline Cellulose (plant-based flow agent)
- Hypromellose (vegetable capsule)
What's NOT in Bonex: This formula contains no artificial colors, flavors, or preservatives. It is manufactured in the USA in a facility that follows Good Manufacturing Practices (GMP).
Why Choose Bonex Bone & Heart Formula?
Scientifically-Informed Formulation: Every ingredient in Bonex was selected based on its role in bone metabolism and cardiovascular support. This isn't a random collection of nutrients—it's a purposeful combination designed around how these compounds work together in human physiology.*
Optimal D3 Dosage: This formula helps maintain healthy Vitamin D levels in the blood. Bonex delivers a key nutrient amount that supports those with limited sunlight exposure, aiding overall wellness.*
Premium K2 Form: We use MK-7 (menaquinone-7) rather than cheaper forms of Vitamin K because MK-7 has superior bioavailability and remains active in your body longer, providing extended benefits from each dose.*
Enhanced Absorption Support: The inclusion of BioPerine® demonstrates our commitment to quality ingredients, which may help improve the uptake of certain nutrients. Optimal utilization is key for support.*
Convenient Twice-Daily Dosing: Rather than requiring you to take multiple products throughout the day, Bonex consolidates your bone and cardiovascular support into one streamlined supplement protocol.*
USA Manufacturing: Bonex is manufactured in the United States in a facility that adheres to Good Manufacturing Practice standards, providing assurance about production quality and consistency.*
How to Use Bonex for Optimal Results*
Standard Dosing: Take one (1) capsule twice daily as a dietary supplement. This twice-daily approach helps maintain more consistent blood levels of these nutrients throughout the day.*
Timing Recommendations: For best absorption, take each capsule 20-30 minutes before a meal with a full glass of water. Since Vitamins D3 and K2 are fat-soluble, taking them before meals that contain some dietary fat may enhance absorption.*
Consistency Matters: Nutritional supplementation works best when taken consistently over time. Make Bonex part of your daily routine by taking it at the same times each day—many users find success with a morning and evening schedule.*
Duration of Use: Bone remodeling is a natural, ongoing process. Individual results vary; however, consistent, long-term use is required for optimal bone support, paired alongside a balanced diet and regular exercise.*
Serving Size: Each serving consists of 1 capsule, taken twice daily. Each bottle contains 60 capsules, providing a 30-day supply when used as directed.
Usage Tips for Maximum Benefits*
Pair with Healthy Fats: Since D3 and K2 are fat-soluble vitamins, consider taking Bonex with meals that include healthy fats like avocado, nuts, olive oil, or fatty fish to optimize absorption.*
Stay Hydrated: Adequate water intake supports all bodily functions, including nutrient transport and utilization. Take your capsules with a full glass of water.*
Complement with Weight-Bearing Exercise: Bone density responds positively to mechanical stress. Combining Bonex supplementation with regular weight-bearing activities like walking, resistance training, or dancing may provide synergistic benefits for bone health.*
Dietary Calcium Sources: While Bonex provides calcium supplementation, continue consuming calcium-rich foods like dairy products, leafy greens, and fortified foods. A multi-pronged approach to calcium intake supports optimal bone health.*
Moderate Caffeine and Sodium: Excessive caffeine and sodium intake may increase calcium excretion. If you consume these regularly, consider moderating intake to support your bone health goals.*
Consider Timing Around Other Supplements: If you take other mineral supplements (like magnesium or zinc), consider spacing them several hours apart from Bonex to minimize potential absorption competition. Consult your healthcare provider for personalized guidance.*
Monitor Vitamin D Levels: Consider having your healthcare provider check your 25-hydroxy Vitamin D blood levels periodically to ensure you're maintaining optimal status (many experts suggest 30-50 ng/mL as a healthy range).*
Quality & Safety Information
Manufacturing Standards: Bonex is produced in the USA in a facility that follows current Good Manufacturing Practice (cGMP) regulations established by the FDA for dietary supplements. These standards help ensure product quality, purity, and accurate labeling.
Quality Ingredients: We source premium-grade ingredients, including bioidentical Vitamin D3 (cholecalciferol), highly bioavailable MK-7 form of Vitamin K2, and patented BioPerine® for enhanced absorption.
Safety Seal: Each bottle features a tamper-evident safety seal. Do not use if this seal is damaged or missing.
Storage Instructions: Store in a cool, dry place away from direct sunlight and moisture. Keep the bottle tightly closed when not in use to maintain product integrity.
Cautions: Do not exceed the recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with known medical conditions should consult a physician before using this or any dietary supplement. This is particularly important for individuals taking blood-thinning medications (like warfarin), as Vitamin K can affect blood clotting.
Keep Out of Reach of Children: This product is intended for adult use only. Store in a location inaccessible to children to prevent accidental ingestion.
Who Will Benefit from Bonex?
Adults Over 40: Bone density naturally begins to decline with age, and the body's ability to produce Vitamin D3 from sunlight decreases. Bonex provides targeted nutritional support during these years when bone health becomes increasingly important.*
Individuals with Limited Sun Exposure: If you work indoors, live in northern latitudes, or consistently use sunscreen, you may not be synthesizing adequate Vitamin D3. Bonex helps fill this nutritional gap.*
Postmenopausal Women: Hormonal changes during menopause can accelerate bone density changes. Supporting bone health with targeted nutrients like those in Bonex may be particularly valuable during this life stage.*
People Seeking Cardiovascular Wellness: Emerging research on Vitamin K2's role in cardiovascular health has made this nutrient increasingly popular among those focused on heart health. Bonex combines K2 with its essential cofactors.*
Active Individuals: Whether you're a weekend warrior or serious athlete, maintaining strong bones supports physical performance and recovery. Bonex provides foundational bone support nutrients.*
Anyone Concerned About Calcium Supplementation: If you've read about concerns regarding calcium supplements and cardiovascular health, Bonex addresses these by including Vitamin K2, which research suggests helps support proper calcium utilization.*
Those Following Plant-Based Diets: Vitamin K2 (MK-7) is primarily found in animal products and fermented foods. Vegans and vegetarians may benefit from supplementation. Additionally, plant-based diets sometimes provide less bioavailable calcium, making supplementation with enhanced absorption (via BioPerine®) particularly valuable.*
Understanding the Science Behind Key Ingredients
Vitamin D3 (Cholecalciferol): The Calcium Absorption Catalyst
Vitamin D3 is technically a hormone rather than a vitamin. When your skin is exposed to UVB radiation from sunlight, it synthesizes D3 from cholesterol. However, modern lifestyles often limit sun exposure, leading to widespread insufficiency.
In your body, D3 undergoes two conversion steps—first in the liver to 25-hydroxyvitamin D, then in the kidneys to the active form, 1,25-dihydroxyvitamin D (calcitriol). This active form increases the expression of calcium-binding proteins in your intestinal cells, enhancing calcium absorption from food by up to 30-40%.*
Research has extensively documented Vitamin D3's role in bone health. A comprehensive review published in the Journal of Clinical Endocrinology & Metabolism examined multiple studies and concluded that Vitamin D supplementation, particularly when combined with calcium, supports bone mineral density, especially in populations at risk for deficiency.
Study Reference: Bolland MJ, Grey A, Avenell A. Effects of vitamin D supplementation on musculoskeletal health: a systematic review, meta-analysis, and trial sequential analysis. Lancet Diabetes Endocrinol. 2018;6(11):847-858. https://pubmed.ncbi.nlm.nih.gov/30293909/
Additionally, research from the Vitamin D Council highlights that maintaining adequate Vitamin D status (blood levels of 30-50 ng/mL) correlates with better overall bone health outcomes compared to deficient status.*
Vitamin K2 (MK-7): The Calcium Director
While Vitamin K1 (phylloquinone) is well-known for its role in blood clotting, Vitamin K2 (menaquinone) has distinct functions in calcium metabolism. K2 activates two critical proteins: osteocalcin and matrix Gla-protein (MGP).
Osteocalcin, produced by bone-building cells called osteoblasts, binds calcium ions and incorporates them into the bone matrix—but only when activated by Vitamin K2. Without sufficient K2, osteocalcin remains inactive, and calcium may not be efficiently deposited in bones.
Matrix Gla-protein (MGP) works in soft tissues, particularly blood vessels, where it helps regulate calcium levels and supports arterial health. When activated by K2, MGP helps prevent inappropriate calcium accumulation in arterial walls.*
The Rotterdam Study, a large population-based cohort study published in The Journal of Nutrition, found that higher dietary intake of Vitamin K2 (but not K1) was associated with better cardiovascular health outcomes. Participants with the highest K2 intake showed better arterial health markers compared to those with low intake.
Study Reference: Geleijnse JM, Vermeer C, Grobbee DE, et al. Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study. J Nutr. 2004;134(11):3100-3105. https://pubmed.ncbi.nlm.nih.gov/15514282/
MK-7 (menaquinone-7) is the preferred form of K2 for supplementation because it has a longer half-life (approximately 72 hours) compared to other forms, meaning it remains bioavailable in your body longer and provides sustained activity from each dose.
Study Reference: Schurgers LJ, Teunissen KJ, Hamulyák K, et al. Vitamin K-containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7. Blood. 2007;109(8):3279-3283. https://pubmed.ncbi.nlm.nih.gov/17158229/
Calcium: The Structural Foundation
Calcium is the most abundant mineral in the human body, with approximately 99% stored in bones and teeth, providing structural support. The remaining 1% circulates in blood and soft tissues, where it plays roles in muscle contraction, nerve signaling, and blood clotting.
Your bones serve as a calcium reservoir. When blood calcium levels drop, your body withdraws calcium from bones through a process called resorption. When blood calcium is adequate, calcium can be deposited back into bones through mineralization. This constant remodeling continues throughout life.
Calcium carbonate, the form used in Bonex, is one of the most concentrated sources of elemental calcium (40% elemental calcium by weight) and is generally well-tolerated when taken with food. The presence of Vitamin D3 in Bonex enhances calcium carbonate absorption significantly.*
Research published in Osteoporosis International has shown that combined calcium and Vitamin D supplementation supports bone mineral density better than calcium alone, particularly in older adults and postmenopausal women.*
Study Reference: Tang BM, Eslick GD, Nowson C, et al. Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: a meta-analysis. Lancet. 2007;370(9588):657-666. https://pubmed.ncbi.nlm.nih.gov/17720017/
BioPerine®: The Absorption Enhancer
BioPerine® is a patented extract from black pepper fruit (Piper nigrum) standardized to contain 95% piperine, the active alkaloid responsible for black pepper's pungency. Research has demonstrated that piperine enhances the bioavailability of various nutrients and compounds.
The mechanism appears to involve multiple pathways: piperine may slow certain metabolic processes in the intestines and liver, giving nutrients more time to be absorbed; it may increase blood flow to the digestive tract; and it may enhance the activity of enzymes involved in nutrient transport.
A study published in Planta Medica found that BioPerine® significantly enhanced the bioavailability of several nutrients, including certain vitamins and amino acids, with improvements ranging from 30% to over 200% depending on the compound tested.
Study Reference: Shoba G, Joy D, Joseph T, et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998;64(4):353-356. https://pubmed.ncbi.nlm.nih.gov/9619120/
By including BioPerine® in the Bonex formula, we aim to maximize your body's ability to absorb and utilize the Vitamin D3 and K2 provided in each capsule.*
Disclaimer:These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
The information provided here is for educational purposes only and is not intended as medical advice. Individual results may vary. Always consult with a qualified healthcare professional before starting any new dietary supplement, especially if you are pregnant, nursing, taking medications (particularly blood thinners), or have a known medical condition. Do not exceed recommended dosage. Keep out of reach of children. Do not use if safety seal is damaged or missing.
The scientific references provided are for informational purposes and do not constitute an endorsement of this product's specific formulation. All health-related decisions should be made in consultation with qualified healthcare professionals based on your individual circumstances.

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