Oxivra Nitric Oxide Booster | L-Arginine + L-Citrulline | Circulation & Muscle Support Capsules | 60 Count
$56.95 USD
Unit price perIn stock
Estimated delivery between December 14 and December 18.
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Additional Information
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Manufacturer's country
USA
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Product amount
60 Capsules
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Gross weight (lb/g)
0.2 lb / 90 g
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Suggested use
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As a dietary supplement, adults take two (2) capsules daily. For best results, take with 68 oz (177-236ml) of water or as directed by healthcare professional.
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Warning
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Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with known medical conditions should consult a physician before using this or any dietary supplement. KEEP OUT OF THE REACH OF CHILDREN. DO NOT USE IF SAFETY SEAL IS DAMAGED OR MISSING. STORE IN A COOL, DRY PLACE.
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Benefits of Oxivra Nitric Oxide Booster | L-Arginine + L-Citrulline | Circulation & Muscle Support Capsules | 60 Count
Discover the key benefits that make our product stand out
Support Healthy Circulation
Enhance Athletic Performance
Boost Energy & Stamina
Support Heart Health
About Oxivra Nitric Oxide Booster | L-Arginine + L-Citrulline | Circulation & Muscle Support Capsules | 60 Count
Oxivra Nitric Oxide – Advanced Circulation & Muscle Performance Support Formula
Premium L-Arginine and L-Citrulline Complex for Healthy Blood Flow and Athletic Performance
Enhance your fitness journey and support your overall wellness with Oxivra Nitric Oxide, a comprehensive circulation support supplement featuring a synergistic blend of L-Arginine Alpha-Ketoglutarate, L-Arginine Hydrochloride, and L-Citrulline DL-Malate—three powerful amino acids that work together to help support your body's natural nitric oxide production, promote healthy blood flow, and contribute to optimal muscle function and exercise performance.*
Nitric oxide (NO) is a naturally occurring molecule in the body that plays a crucial role in vasodilation—the widening of blood vessels—which helps support healthy circulation and nutrient delivery throughout the body. As we age or face lifestyle challenges, natural nitric oxide production may decline, potentially affecting circulation, exercise capacity, and overall vitality. Oxivra Nitric Oxide provides targeted nutritional support to help maintain healthy nitric oxide levels through precursor amino acids that your body can convert into this vital molecule.*
This athletic performance supplement delivers a potent combination of three complementary amino acids in convenient capsule form, making it easy to support your circulation, muscle function, workout performance, and recovery as part of your daily fitness and wellness routine.* Whether you're an athlete seeking to optimize training results, a fitness enthusiast wanting to support exercise performance, or someone simply interested in supporting healthy circulation and cardiovascular wellness, this formula provides comprehensive support for your goals.*
Made in the USA with quality ingredients and a vegetable capsule for easy absorption, this supplement represents a convenient, effective way to help support your body's natural nitric oxide production and promote the healthy blood flow that's essential for delivering oxygen and nutrients to working muscles and tissues throughout your body.*
Top 4 Pain Points & How This Supplement May Help
Pain Point #1: Declining Exercise Performance and Training Plateaus
Exercise performance limitations and training plateaus frustrate countless fitness enthusiasts and athletes who dedicate significant time and effort to their workouts but struggle to see continued progress or improvements in strength, endurance, power output, and overall athletic capacity. Multiple factors contribute to exercise performance challenges including inadequate nutrient delivery to working muscles during training, insufficient oxygen supply to muscle tissue during intense exercise, limited blood flow restricting the removal of metabolic waste products like lactate that contribute to fatigue, poor muscle pump and vascularity during resistance training, reduced exercise capacity and endurance during cardiovascular activities, longer recovery times between training sessions, difficulty achieving progressive overload in strength training programs, and the natural decline in nitric oxide production that occurs with aging—typically beginning in the 20s and 30s and accelerating thereafter. As nitric oxide levels decline, blood vessels may not dilate as efficiently, potentially limiting the increased blood flow that working muscles require during exercise to receive oxygen, glucose, amino acids, and other nutrients while removing carbon dioxide, lactate, and other metabolic byproducts. This can manifest as hitting a wall during workouts, feeling like muscles aren't getting a good pump, experiencing premature fatigue, struggling to increase weights or reps despite consistent training, or feeling like workouts that were once manageable now feel significantly more challenging. Many people don't realize that circulation and blood flow play such critical roles in exercise performance, or that supporting nitric oxide production through targeted amino acid supplementation may help address these training challenges.
How Oxivra Nitric Oxide Supports You:
This exercise performance formula is specifically designed to help support your body's natural nitric oxide production through three synergistic amino acid precursors that work together to promote healthy blood flow and circulation during physical activity.* L-Arginine Alpha-Ketoglutarate (AAKG) is a compound combining the amino acid L-arginine with alpha-ketoglutarate, creating a form that's popular among athletes and bodybuilders for its potential to support exercise performance.* L-arginine serves as a direct precursor to nitric oxide—your body converts arginine into nitric oxide through enzymes called nitric oxide synthases (NOS).* By providing supplemental arginine, particularly in the alpha-ketoglutarate form which some research suggests may have enhanced bioavailability, this formula helps ensure your body has adequate substrate to support nitric oxide production, particularly during times of increased demand like exercise.* The alpha-ketoglutarate component is also involved in the Krebs cycle (cellular energy production), potentially providing additional benefits for exercise metabolism.* L-Arginine Hydrochloride provides additional arginine in a highly stable, water-soluble form that's well-absorbed and contributes to the total arginine pool available for nitric oxide synthesis.* Research has investigated arginine supplementation's potential to support exercise performance, endurance, strength gains, and recovery through its role in promoting vasodilation and increased blood flow to working muscles.* L-Citrulline DL-Malate is perhaps the most important ingredient in this formula—citrulline is another amino acid that's actually converted into arginine in the body, but with some unique advantages.* Studies suggest that citrulline supplementation may increase blood arginine levels more effectively than arginine supplementation alone because citrulline bypasses first-pass metabolism in the liver, gets absorbed more efficiently, and provides sustained arginine elevation over time.* The malate component (malic acid) is involved in energy production and may help support exercise performance through its role in the Krebs cycle and ATP production.* Research has investigated citrulline malate's potential to support exercise performance, reduce muscle fatigue, improve training volume, and enhance recovery.* When these three amino acids work together—providing both direct arginine and the citrulline that converts to arginine—they create a comprehensive approach to supporting nitric oxide production and the healthy vasodilation that can help increase blood flow to working muscles during exercise.* This enhanced blood flow may help deliver more oxygen, glucose, amino acids, creatine, and other nutrients to muscle tissue while facilitating the removal of metabolic waste products, potentially supporting improved exercise performance, better muscle pump, enhanced endurance, and more effective training sessions. The vegetable capsule form provides convenient dosing that can be timed around workouts—many people take nitric oxide supplements 30-60 minutes before training to support blood flow during exercise. With consistent use as part of a comprehensive training program that includes progressive overload, proper nutrition, adequate recovery, and appropriate training volume and intensity, this formula helps provide the nutritional support your cardiovascular and muscular systems need to perform optimally during challenging workouts.
Pain Point #2: Suboptimal Muscle Growth and Recovery
Limited muscle growth despite consistent training and prolonged recovery times between workouts represent major frustrations for anyone engaged in resistance training, bodybuilding, or strength sports. Building muscle requires not just the training stimulus itself but also adequate nutritional support for the complex processes of muscle protein synthesis, tissue repair, and adaptation that occur during recovery periods between workouts. Multiple factors influence muscle growth potential including inadequate nutrient delivery to muscle tissue, insufficient amino acid availability during the critical post-workout recovery window, suboptimal blood flow limiting the transport of anabolic hormones like testosterone and growth hormone to target tissues, reduced oxygen and nutrient supply to muscles during and after training, inadequate removal of metabolic waste products that can interfere with recovery processes, insufficient muscle protein synthesis rates despite adequate protein intake, poor cellular hydration and muscle cell volume, limited satellite cell activation and muscle repair processes, and declining anabolic hormone levels and nitric oxide production with aging. The "muscle pump" experienced during resistance training—that satisfying feeling of fullness and tightness in trained muscles—isn't just cosmetic; it reflects increased blood flow, cellular swelling, and nutrient delivery that may play roles in triggering anabolic signaling pathways. Without adequate blood flow and circulation, muscles may not receive optimal amounts of the amino acids, glucose, oxygen, creatine, hormones, and other compounds they need for maximal protein synthesis and growth. Recovery between training sessions may take longer, muscle soreness may persist, and the anabolic response to training may be suboptimal. Many people focus exclusively on protein intake and training intensity while overlooking the critical importance of circulation and nutrient delivery for maximizing training adaptations and muscle growth.
How Oxivra Nitric Oxide Supports You:
This muscle support formula is designed to help promote the healthy blood flow and nutrient delivery that are essential for supporting muscle growth, recovery, and adaptation to resistance training.* L-Arginine, as a precursor to nitric oxide, helps support vasodilation and increased blood flow to muscle tissue, potentially enhancing the delivery of amino acids, glucose, oxygen, creatine, and other nutrients that muscles need for growth and recovery.* Enhanced blood flow during and after training may help create an environment more conducive to muscle protein synthesis by ensuring working muscles have abundant access to the building blocks and energy substrates they need.* Research has investigated arginine's potential role in supporting muscle protein synthesis, enhancing growth hormone responses to exercise, and contributing to recovery processes.* The improved circulation may also help facilitate the removal of metabolic waste products like lactate, ammonia, and hydrogen ions that accumulate during intense training and can interfere with muscle function and recovery if not efficiently cleared.* L-Citrulline DL-Malate has been specifically studied for its potential to support muscle recovery, reduce muscle soreness following exercise, and improve training capacity.* Some research suggests citrulline malate supplementation may help reduce muscle fatigue, support higher training volumes (more sets and reps), and enhance recovery between training sessions—all factors that can contribute to better long-term training adaptations and muscle growth.* The malate component supports energy production pathways and may help reduce ammonia accumulation during exercise, potentially contributing to reduced fatigue and better performance during high-volume training.* The enhanced blood flow and "muscle pump" supported by this formula isn't just about aesthetics—the cellular swelling and increased blood volume in muscle tissue may trigger mechanoreceptors and contribute to anabolic signaling pathways including mTOR activation, which is central to muscle protein synthesis and growth.* Some research has explored the concept that cell volume and cellular hydration status influence protein synthesis rates.* L-Arginine Hydrochloride provides additional arginine to support sustained nitric oxide production throughout the day and during recovery periods between workouts.* The amino acids in this formula may also serve other roles beyond nitric oxide production—arginine, for instance, is involved in creatine synthesis, immune function, wound healing, and protein metabolism.* By helping to support optimal blood flow and nutrient delivery to muscle tissue, this supplement contributes to creating the physiological conditions that support muscle growth, recovery, and positive adaptations to resistance training.* The convenient twice-daily dosing allows you to maintain consistent amino acid levels to support circulation and recovery on both training and rest days, as recovery and adaptation processes continue around the clock, not just during workouts. When combined with progressive resistance training, adequate protein intake (typically 1.6-2.2g per kg body weight for muscle growth), sufficient calories, quality sleep, and appropriate recovery practices, this formula helps provide nutritional support for maximizing your body's muscle-building and recovery potential.*
Pain Point #3: Cardiovascular Health Concerns and Circulation Issues
Cardiovascular wellness and healthy circulation are fundamental to overall health, vitality, energy levels, and quality of life, yet many people experience concerns related to circulation, cardiovascular function, or simply want to proactively support their heart and vascular health as they age. The cardiovascular system—comprising the heart, blood vessels, and circulatory pathways—is responsible for delivering oxygen, nutrients, hormones, immune cells, and other vital substances to every cell in the body while removing carbon dioxide, metabolic waste, and other byproducts. Healthy circulation requires proper blood vessel function, particularly endothelial health (the inner lining of blood vessels), which is critically dependent on nitric oxide production. Multiple factors can compromise cardiovascular health and circulation including natural decline in nitric oxide production with aging (estimated 10-12% decrease per decade after age 40), sedentary lifestyle and lack of regular physical activity, poor dietary patterns high in processed foods and low in nitric oxide-supporting nutrients, oxidative stress and inflammation, elevated blood pressure, unhealthy cholesterol levels, excess weight particularly around the midsection, smoking and environmental toxins, chronic stress, poor sleep, and genetic predisposition. When circulation is compromised, people may experience cold hands and feet, reduced energy and stamina, difficulty with physical activities, poor exercise tolerance, longer recovery from exertion, reduced cognitive function and mental clarity, and general feelings of diminished vitality. Nitric oxide plays such a crucial role in cardiovascular health that the scientists who discovered its role as a signaling molecule in the cardiovascular system were awarded the Nobel Prize in Physiology or Medicine in 1998. Without adequate nitric oxide production, blood vessels can't dilate properly, potentially affecting blood pressure, circulation, oxygen delivery, and overall cardiovascular function.
How Oxivra Nitric Oxide Supports You:
This cardiovascular support formula is specifically designed to help promote healthy nitric oxide production and support the circulation and blood flow that are fundamental to cardiovascular wellness and whole-body health.* Nitric oxide is one of the most important signaling molecules in the cardiovascular system, helping to regulate vascular tone, support healthy blood pressure already within normal range, promote endothelial health, contribute to normal platelet function, and support overall cardiovascular function.* By providing the amino acid precursors your body needs to produce nitric oxide—L-Arginine and L-Citrulline—this supplement helps support your body's natural mechanisms for maintaining healthy blood vessel function and circulation.* L-Arginine is converted by nitric oxide synthase enzymes into nitric oxide and L-citrulline in a process that's fundamental to vascular health.* Research has extensively investigated arginine's potential role in supporting cardiovascular health, promoting healthy endothelial function, helping to maintain healthy blood pressure already within normal range, and contributing to overall circulatory wellness.* The endothelium—the single-cell layer lining the inside of blood vessels—is critically dependent on nitric oxide for proper function, and endothelial health is considered a key marker of cardiovascular wellness.* L-Citrulline DL-Malate supports arginine levels and nitric oxide production while potentially offering advantages over arginine supplementation alone, including better absorption, sustained elevation of arginine levels, and bypass of first-pass hepatic metabolism.* Studies have investigated citrulline's potential to support cardiovascular health, enhance blood flow, and promote healthy vascular function.* The combination of multiple arginine forms plus citrulline creates a comprehensive approach to supporting nitric oxide production throughout the day, helping to maintain the healthy vascular function that's essential for optimal circulation to all organs and tissues—brain, heart, kidneys, muscles, skin, and beyond.* Improved circulation supports not just cardiovascular health but overall vitality, energy levels, cognitive function, sexual health, and physical performance—essentially every system in the body benefits from optimal blood flow and oxygen delivery.* The vegetable capsule form provides convenient, consistent supplementation that can be incorporated into daily wellness routines to support long-term cardiovascular health.* This is particularly important because nitric oxide production declines with age, and proactive nutritional support may help maintain healthy levels and support vascular health as you age.* The formula's support for healthy circulation may also contribute to maintaining healthy blood pressure already within normal range, supporting the elasticity and flexibility of blood vessel walls, promoting efficient nutrient and oxygen delivery throughout the body, and contributing to overall cardiovascular resilience. While this supplement provides valuable nutritional support for circulation and cardiovascular wellness, it works best as part of a comprehensive heart-healthy lifestyle that includes regular physical activity (which itself promotes nitric oxide production), a diet rich in fruits, vegetables, and whole foods, stress management, adequate sleep, maintaining healthy weight, avoiding smoking, and regular check-ups with healthcare providers for monitoring cardiovascular health markers.*
Pain Point #4: Low Energy, Fatigue, and Reduced Physical Stamina
Persistent low energy, fatigue, and reduced stamina affect millions of people, limiting their ability to fully engage in work, exercise, daily activities, hobbies, and social interactions. While fatigue can stem from numerous causes including inadequate sleep, nutritional deficiencies, stress, medical conditions, or lifestyle factors, one often-overlooked contributor is suboptimal circulation and oxygen delivery to tissues throughout the body. Every cell in the body requires oxygen and nutrients to produce ATP (adenosine triphosphate)—the cellular energy currency—through aerobic metabolism. When circulation is compromised or blood flow is restricted, cells may not receive optimal amounts of oxygen and glucose, potentially affecting energy production and contributing to feelings of fatigue, reduced physical capacity, mental fog, and general low vitality. This is particularly noticeable during physical exertion when muscles dramatically increase their oxygen and nutrient demands—if blood flow can't increase adequately to meet these demands, performance suffers and fatigue sets in more quickly. Many people experiencing persistent fatigue focus on stimulants like caffeine or energy drinks for temporary boosts, but these don't address the underlying issue of whether cells are receiving adequate oxygen and nutrients for efficient energy production. Similarly, some people experience what feels like "hitting a wall" during exercise or daily activities, where energy suddenly plummets and continuing feels extremely difficult. The cardiovascular system's ability to deliver oxygenated blood efficiently throughout the body is fundamental to maintaining energy levels, and supporting healthy nitric oxide production—which promotes vasodilation and blood flow—may help address circulation-related contributions to fatigue and low stamina.
How Oxivra Nitric Oxide Supports You:
This energy and vitality support formula is designed to help promote the healthy circulation and blood flow that are essential for optimal oxygen and nutrient delivery to all cells and tissues, potentially contributing to sustained energy levels and improved physical stamina.* Nitric oxide's primary role in vasodilation means it helps blood vessels relax and widen, allowing increased blood flow in response to the body's needs—particularly during physical activity or mental exertion when energy demands spike.* By providing the amino acid precursors needed to support nitric oxide production, this supplement helps ensure your cardiovascular system can respond appropriately to varying energy demands throughout the day.* L-Arginine and L-Citrulline work together to support the nitric oxide production that enables efficient oxygen and nutrient delivery—when blood can flow more freely through dilated vessels, oxygen-rich blood reaches working muscles, the brain, and other tissues more effectively, supporting the aerobic energy production that powers nearly all cellular activities.* This may help contribute to better energy levels, reduced feelings of fatigue, improved mental clarity and focus (as the brain receives better oxygen and glucose supply), enhanced exercise tolerance and stamina, and overall improved physical and mental vitality.* L-Citrulline DL-Malate deserves special attention for energy support because the malate component is directly involved in the Krebs cycle (citric acid cycle)—a fundamental metabolic pathway for ATP production in mitochondria.* Malic acid plays a role in the energy production process, and some research has investigated citrulline malate's potential to support ATP production, reduce fatigue during exercise, and enhance recovery between efforts.* The combination may help support both the delivery of oxygen and nutrients to cells (through improved circulation) and the actual cellular energy production processes themselves.* Studies have investigated citrulline malate's effects on exercise performance, finding potential benefits for reducing fatigue, increasing total work performed, and improving recovery—all indicators of better energy availability and utilization.* For people experiencing fatigue related to suboptimal circulation or oxygen delivery, supporting nitric oxide production may help improve the efficiency with which the cardiovascular system delivers the oxygen and nutrients that cells need for energy production.* This won't replace the need for adequate sleep, proper nutrition, stress management, and addressing any underlying medical conditions contributing to fatigue, but it provides targeted nutritional support for one important factor—circulation and oxygen delivery.* The twice-daily dosing helps maintain consistent amino acid availability to support nitric oxide production throughout the day, contributing to sustained circulatory support rather than just around workout times.* Whether you're an athlete seeking better training energy and endurance, a busy professional wanting sustained mental and physical energy throughout workday demands, or someone simply wanting to feel more vital and energetic in daily life, supporting healthy circulation through nitric oxide precursor supplementation represents a physiologically sound approach to nutritional support for energy and stamina. The formula's circulation benefits may also contribute to faster recovery after exertion—when blood flow is optimized, the removal of metabolic waste products and delivery of recovery nutrients happens more efficiently, potentially reducing the fatigue that lingers after intense physical or mental effort.*
Why Choose Oxivra Nitric Oxide?
Synergistic Amino Acid Complex
Three Complementary Nitric Oxide Precursors
- L-Arginine Alpha-Ketoglutarate: Direct NO precursor with enhanced bioavailability form
- L-Arginine Hydrochloride: Additional arginine in stable, absorbable form
- L-Citrulline DL-Malate: Converts to arginine with sustained elevation and energy support
- Comprehensive Approach: Multiple pathways for supporting NO production
- Research-Backed: Individually studied ingredients with scientific support
Multi-Benefit Support
Versatile Health and Performance Benefits
- Supports healthy circulation and blood flow
- Promotes muscle performance during exercise
- Contributes to muscle growth and recovery
- Helps maintain cardiovascular wellness
- Supports energy production and stamina
- Promotes healthy nutrient delivery throughout body
Quality Manufacturing
USA-Made with Quality Standards
- Manufactured in USA facilities
- Vegetable capsule for easy absorption
- Clean, simple ingredient list
- No unnecessary fillers or additives
- Quality amino acid sources
Convenient Daily Use
✓ Simple Dosing – Just 2 capsules daily ✓ Flexible Timing – Take with water anytime ✓ Vegetable Capsules – Easy to swallow ✓ Travel-Friendly – Convenient for on-the-go ✓ Easy Integration – Fits seamlessly into any routine
Complete Ingredient Profile
Active Ingredients Per Serving (2 Capsules):
- L-Arginine Alpha-Ketoglutarate (AAKG)
- L-Arginine Hydrochloride
- L-Citrulline DL-Malate
Other Ingredients:
- Cellulose (vegetable capsule)
- Brown Rice Flour
Product Specifications:
- Product Amount: 60 capsules
- Gross Weight: 0.2 lb / 90 g
- Manufactured In: USA
- Form: Vegetable capsules
- Serving Size: 2 capsules
- Servings Per Container: 30
How to Use for Optimal Results
Simple Dosing Instructions:
Suggested Use: As a dietary supplement, adults take two (2) capsules daily. For best results, take with 6-8 oz (177-236ml) of water or as directed by healthcare professional.
Optimal Timing Strategies:
Pre-Workout: Take 30-60 minutes before training to support blood flow and performance during exercise
Morning: Take with breakfast to support circulation and energy throughout the day
Divided Dose: Take 1 capsule twice daily (morning and pre-workout) for sustained support
Consistency: Daily use is important—benefits build over time with regular supplementation
Usage Tips for Maximum Benefits
✨ Stay Hydrated: Drink plenty of water throughout the day for optimal circulation
✨ Time Around Workouts: Many users prefer taking 30-60 minutes pre-workout for performance support
✨ Consistent Daily Use: Benefits accumulate with regular supplementation—don't skip days
✨ Combine with Exercise: Physical activity itself promotes nitric oxide production—supplement and exercise work synergistically
✨ Healthy Diet: Support results with diet rich in nitrate-containing vegetables (beets, leafy greens, arugula)
✨ Adequate Sleep: Recovery and circulation benefit from quality sleep
✨ Avoid Mouthwash: Some mouthwashes can interfere with nitric oxide production—consider limiting use
Quality & Safety Information
Important Safety Guidelines:
Age Restrictions
- Adults Only: This product is formulated for adults
- Children Under 18: Should consult a physician before use
- Not for Pediatric Use: Not intended for children without medical supervision
Special Populations
- Pregnant or Nursing Mothers: Must consult a physician before use
- Medical Conditions: Individuals with cardiovascular conditions, blood pressure concerns, or other medical conditions should consult physician before use
- Medications: Consult healthcare provider if taking blood pressure medications, erectile dysfunction medications, or other prescriptions
Dosage Safety
- Do Not Exceed Recommended Dose: Follow suggested use of 2 capsules daily
- Medical Supervision: Use as directed by healthcare professional
Storage & Handling
- Keep Out of Reach of Children: Store safely away from young children
- Safety Seal: Do not use if safety seal is damaged or missing
- Storage Conditions: Store in a cool, dry place
Who Will Benefit from This Product?
Oxivra Nitric Oxide is ideal for:
- Athletes and bodybuilders seeking to support exercise performance
- Fitness enthusiasts wanting to enhance workout results and muscle pump
- Individuals looking to support healthy circulation and blood flow
- Active adults seeking to maintain cardiovascular wellness
- People experiencing exercise performance plateaus
- Those wanting to support muscle growth and recovery
- Individuals seeking increased training endurance and stamina
- Anyone wanting to support healthy blood flow and nutrient delivery
- Older adults concerned about declining nitric oxide production
- People seeking natural circulation support through amino acids
- Those wanting pre-workout support without stimulants
- Anyone interested in cardiovascular health maintenance
Understanding Key Ingredients
L-Arginine: The Direct NO Precursor
L-Arginine is a semi-essential amino acid that serves as the direct substrate for nitric oxide production through the nitric oxide synthase enzyme pathway.
Key properties:
- Nitric Oxide Precursor: Directly converted to NO by NOS enzymes
- Vasodilation Support: Promotes blood vessel relaxation and widening
- Cardiovascular Research: Extensively studied for circulation and heart health
- Exercise Performance: Investigated for potential performance benefits
- Multiple Forms: Provided as both AAKG and HCl for comprehensive support
L-Arginine Alpha-Ketoglutarate (AAKG): Enhanced Form
AAKG combines L-arginine with alpha-ketoglutarate, potentially offering enhanced bioavailability and additional benefits.
Key properties:
- Enhanced Absorption: Some research suggests improved bioavailability
- Dual Benefits: Arginine for NO production, AKG for energy metabolism
- Popular with Athletes: Commonly used in sports nutrition
- Krebs Cycle: AKG component involved in cellular energy production
- Research Interest: Studied for exercise performance applications
L-Citrulline DL-Malate: The Superior NO Booster
L-Citrulline is an amino acid that converts to L-arginine in the body, but may be more effective than direct arginine supplementation.
Key properties:
- Converts to Arginine: Provides sustained arginine elevation
- Better Absorption: Bypasses first-pass hepatic metabolism
- Sustained Effects: Longer-lasting arginine increases than arginine alone
- Exercise Research: Well-studied for performance and fatigue reduction
- Malate Benefits: Malic acid supports energy production pathways
Research suggests citrulline supplementation may increase plasma arginine levels more effectively than equivalent arginine supplementation.
The Synergistic Combination
The formula's combination of arginine (two forms) plus citrulline creates multi-pathway support:
- Immediate: Arginine provides direct substrate for NO production
- Sustained: Citrulline converts to arginine for prolonged elevation
- Comprehensive: Multiple forms ensure consistent amino acid availability
- Complementary: Each ingredient supports the others' effectiveness
Research References
The ingredients in this formula are based on established research regarding nitric oxide, amino acid metabolism, exercise physiology, and cardiovascular health. For more information on L-arginine, L-citrulline, and nitric oxide biology, we encourage you to explore scientific literature:
Key Research Areas:
- Nitric Oxide and Cardiovascular Health: Search scientific databases for "nitric oxide endothelial function," "NO cardiovascular health," "nitric oxide vascular health," and "endothelium nitric oxide"
- Arginine Supplementation: Research on "L-arginine exercise performance," "arginine nitric oxide," "AAKG athletic performance," and "arginine cardiovascular"
- Citrulline Research: Studies on "citrulline malate exercise," "citrulline arginine conversion," "citrulline performance," and "citrulline fatigue"
- Exercise Performance: Research available on "nitric oxide exercise," "arginine muscle," "citrulline endurance," and "NO athletic performance"
Recommended Research Databases:
- PubMed (www.ncbi.nlm.nih.gov/pubmed) - Comprehensive database of biomedical research
- Journal of the International Society of Sports Nutrition - Sports supplementation research
- American Journal of Physiology - Exercise physiology and cardiovascular research
- Nitric Oxide: Biology and Chemistry - Specialized journal on NO research
- European Journal of Applied Physiology - Exercise and performance research
Notable Research Areas:
- 1998 Nobel Prize: Recognition of nitric oxide as a signaling molecule in cardiovascular system (Furchgott, Ignarro, Murad)
- Citrulline Studies: Research showing citrulline supplementation may increase arginine levels more effectively than arginine alone
- AAKG Research: Studies investigating alpha-ketoglutarate's potential benefits for exercise performance
- Exercise and NO: Research on how exercise stimulates nitric oxide production and how supplementation may support this process
Support your circulation. Enhance your performance. Optimize your health. Experience Oxivra Nitric Oxide.
Frequently Asked Questions
REQUIRED FDA/FTC DISCLAIMER:
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This product is a dietary supplement intended to provide nutritional support for circulation, exercise performance, and overall wellness as part of a healthy lifestyle. It is not a drug and is not intended to replace medical treatment, diagnosis, or cure any medical condition. Results may vary significantly based on individual factors including age, health status, fitness level, diet, training program, genetics, consistency of use, and other variables. This supplement works best when combined with regular exercise, balanced nutrition, adequate protein intake, sufficient hydration, quality sleep, and other healthy lifestyle practices. The information provided is for educational purposes only and is not intended as a substitute for advice from your physician or other healthcare professional. You should not use this information for self-diagnosis or for treating a health problem or disease. Consult with a healthcare professional before starting any dietary supplement or new exercise program, especially if you are pregnant, nursing, under 18, have a known medical condition (particularly cardiovascular conditions, blood pressure concerns, kidney disease, or bleeding disorders), are scheduled for surgery, or are taking prescription medications (particularly blood pressure medications, erectile dysfunction medications, blood thinners, or medications for cardiovascular conditions). Arginine and citrulline may affect blood pressure and vascular function. Individual results may vary, and we make no guarantees regarding specific outcomes, muscle growth, performance improvements, or other benefits. If you experience any adverse reactions including dizziness, nausea, or other discomfort, discontinue use and consult a healthcare professional immediately. Keep out of reach of children. Do not use if safety seal is damaged or missing. Store in a cool, dry place.
Important Safety & Usage Warning:
Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Keep out of reach of children. Store in a cool, dry place.
Disclaimer:*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This product is a dietary supplement intended to provide nutritional support for circulation, exercise performance, and overall wellness as part of a healthy lifestyle. It is not a drug and is not intended to replace medical treatment, diagnosis, or cure any medical condition. Results may vary significantly based on individual factors including age, health status, fitness level, diet, training program, genetics, consistency of use, and other variables. This supplement works best when combined with regular exercise, balanced nutrition, adequate protein intake, sufficient hydration, quality sleep, and other healthy lifestyle practices. The information provided is for educational purposes only and is not intended as a substitute for advice from your physician or other healthcare professional. You should not use this information for self-diagnosis or for treating a health problem or disease. Consult with a healthcare professional before starting any dietary supplement or new exercise program, especially if you are pregnant, nursing, under 18, have a known medical condition (particularly cardiovascular conditions, blood pressure concerns, kidney disease, or bleeding disorders), are scheduled for surgery, or are taking prescription medications (particularly blood pressure medications, erectile dysfunction medications, blood thinners, or medications for cardiovascular conditions). Arginine and citrulline may affect blood pressure and vascular function. Individual results may vary, and we make no guarantees regarding specific outcomes, muscle growth, performance improvements, or other benefits. If you experience any adverse reactions including dizziness, nausea, or other discomfort, discontinue use and consult a healthcare professional immediately. Keep out of reach of children. Do not use if safety seal is damaged or missing. Store in a cool, dry place.

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